About: PLASMA FREE METANEPHRINES AS DIAGNOSTIC MARKERS OF PHEOCHROMOCYTOMA

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: PLASMA FREE METANEPHRINES AS DIAGNOSTIC MARKERS OF PHEOCHROMOCYTOMA Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.chemicke-listy.cz/docs/full/2013_s3_s420-s453.pdf
Description	Quantitative determination of catecholamines and their O-methyl metabolites plays an important role in the diagnosis of pheochromocytoma (PHEO) - adrenal medulla tumour. This kind of tumour synthesizes, stocks, metabolizes and mostly secretes catecholamines. For this reason it is possible to use elevated concentrations of catecholamines and their metabolic products from plasma and urine as diagnostic markers of this tumour. Determination of metanephrines is often preferred against determination of catecholamines regarding the diagnosis of PHEO. Tumour cells produce free metanephrines continuously and irrespective of the release of catecholamines. The project aims to develop a new kit for the determination of plasma metanephrines. Solid phase extraction (SPE) was used for the pre-treatment of plasma samples. The determination was performed by high performance liquid chromatography with electrochemical detection (HPLC-ED). Quantitative determination of catecholamines and their O-methyl metabolites plays an important role in the diagnosis of pheochromocytoma (PHEO) - adrenal medulla tumour. This kind of tumour synthesizes, stocks, metabolizes and mostly secretes catecholamines. For this reason it is possible to use elevated concentrations of catecholamines and their metabolic products from plasma and urine as diagnostic markers of this tumour. Determination of metanephrines is often preferred against determination of catecholamines regarding the diagnosis of PHEO. Tumour cells produce free metanephrines continuously and irrespective of the release of catecholamines. The project aims to develop a new kit for the determination of plasma metanephrines. Solid phase extraction (SPE) was used for the pre-treatment of plasma samples. The determination was performed by high performance liquid chromatography with electrochemical detection (HPLC-ED). (en)
Title	PLASMA FREE METANEPHRINES AS DIAGNOSTIC MARKERS OF PHEOCHROMOCYTOMA PLASMA FREE METANEPHRINES AS DIAGNOSTIC MARKERS OF PHEOCHROMOCYTOMA (en)
skos:prefLabel	PLASMA FREE METANEPHRINES AS DIAGNOSTIC MARKERS OF PHEOCHROMOCYTOMA PLASMA FREE METANEPHRINES AS DIAGNOSTIC MARKERS OF PHEOCHROMOCYTOMA (en)
skos:notation	RIV/00216208:11110/13:10210260!RIV14-MPO-11110___
http://linked.open...avai/riv/aktivita	P V
http://linked.open...avai/riv/aktivity	P(FR-TI4/331), V
http://linked.open...iv/cisloPeriodika	Supplement 3
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Vránková, Alice
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	96408
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/13:10210260
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	PHEOCHROMOCYTOMA; MARKERS; DIAGNOSTIC; PLASMA FREE METANEPHRINES (en)
http://linked.open.../riv/klicoveSlovo	PHEOCHROMOCYTOMA PLASMA FREE METANEPHRINES MARKERS DIAGNOSTIC
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[00D23726ADE0]
http://linked.open...i/riv/nazevZdroje	Chemické listy
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	*The development of a plasma free metanephrine analysis kit
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	107
http://linked.open...iv/tvurceVysledku	Brabcová Vránková, Alice Antal, Miroslav Bartos, Michal Horna, Ales Nyvltova, Zora Pilarova, Michaela Portychova, Lenka Vermousek, Ivan
http://linked.open...ain/vavai/riv/wos	000328730800056
issn	0009-2770
number of pages	3 (xsd:int)
http://localhost/t...ganizacniJednotka	11110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software