About: Curcumin-containing liposomes stabilized by thin layers of chitosan derivatives

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Curcumin-containing liposomes stabilized by thin layers of chitosan derivatives Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1016/j.colsurfb.2013.03.059
Description	Stable vesicles for efficient curcumin encapsulation, delivery and controlled release have been obtained by coating ofliposomes with thin layer of newly synthesized chitosan derivatives. Three different derivatives of chitosan were obtained and studied: the cationic (by introduction of the stable, quaternary ammonium groups), the hydrophobic (by attachment of N-dodecyl groups) and cationic-hydrophobic one (containing both quaternary ammonium and N-dodecyl groups). Zeta potential measurements confirmed effective coating of liposomes with all these chitosan derivatives. The liposomes coated with cationic-hydrophobic chitosan derivative are the most promising curcumin carriers; they can easily penetrate cell membrane and release curcumin in a controlled manner. Biological studies indicated that such systems are non-toxic for murine fibroblasts (NIH3T3) while toxic toward murine melanoma (B16F10) cell line. Stable vesicles for efficient curcumin encapsulation, delivery and controlled release have been obtained by coating ofliposomes with thin layer of newly synthesized chitosan derivatives. Three different derivatives of chitosan were obtained and studied: the cationic (by introduction of the stable, quaternary ammonium groups), the hydrophobic (by attachment of N-dodecyl groups) and cationic-hydrophobic one (containing both quaternary ammonium and N-dodecyl groups). Zeta potential measurements confirmed effective coating of liposomes with all these chitosan derivatives. The liposomes coated with cationic-hydrophobic chitosan derivative are the most promising curcumin carriers; they can easily penetrate cell membrane and release curcumin in a controlled manner. Biological studies indicated that such systems are non-toxic for murine fibroblasts (NIH3T3) while toxic toward murine melanoma (B16F10) cell line. (en)
Title	Curcumin-containing liposomes stabilized by thin layers of chitosan derivatives Curcumin-containing liposomes stabilized by thin layers of chitosan derivatives (en)
skos:prefLabel	Curcumin-containing liposomes stabilized by thin layers of chitosan derivatives Curcumin-containing liposomes stabilized by thin layers of chitosan derivatives (en)
skos:notation	RIV/00216208:11110/13:10194767!RIV14-GA0-11110___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GBP302/12/G157)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Bednár, Ján
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	67507
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/13:10194767
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Carrier; Coating; Liposome; Curcumin; Chitosan derivative (en)
http://linked.open.../riv/klicoveSlovo	Chitosan derivative Coating Liposome Carrier Curcumin
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[F16B71CEA7A6]
http://linked.open...i/riv/nazevZdroje	Colloids and Surfaces B: Biointerfaces
http://linked.open...in/vavai/riv/obor	JI
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Dynamics and Organization of Chromosomes in the Cell Cycle and during Differentiation under Normal and Pathological Conditions
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	109
http://linked.open...iv/tvurceVysledku	Bednár, Ján Nowakowska, Maria Dulak, Jozef Jozkowicz, Alicja Bielska, Dorota Gzyl-Malcher, Barbara Karewicz, Anna Loboda, Agnieszka
http://linked.open...ain/vavai/riv/wos	000320413300044
issn	0927-7765
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.colsurfb.2013.03.059
http://localhost/t...ganizacniJednotka	11110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software