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Description
  • Objectives: The aim of our work was to implement a prototype of a decision support system which has the form of a web-based classification service. Because the data analysis component of decision support systems often happens to be unsuitable for high-dimensional data, special attention must be paid to the sophisticated selection of the most relevant variables before learning the classification rule. Methods: We implemented a prototype of a diagnostic decision support system called SIR. The system has the ability to select the most relevant variables based on a set of high-dimensional measurements by means of a forward procedure optimizing a decision-making criterion. This allows to learn a reliable classification rule. Results: The implemented prototype was tested on a sample of patients involved in a cardiology study. We used SIR to perform an information extraction from a cardiological clinical study containing both clinical and gene expression data. The classification performance was evaluated by means of a cross validation study. Conclusions: The proposed classification system can be useful for clinicians in primary care to support their decision-making tasks with relevant information extracted from any available clinical study. It is especially suitable for analyzing high-dimensional data, e.g. gene expression measurements.
  • Objectives: The aim of our work was to implement a prototype of a decision support system which has the form of a web-based classification service. Because the data analysis component of decision support systems often happens to be unsuitable for high-dimensional data, special attention must be paid to the sophisticated selection of the most relevant variables before learning the classification rule. Methods: We implemented a prototype of a diagnostic decision support system called SIR. The system has the ability to select the most relevant variables based on a set of high-dimensional measurements by means of a forward procedure optimizing a decision-making criterion. This allows to learn a reliable classification rule. Results: The implemented prototype was tested on a sample of patients involved in a cardiology study. We used SIR to perform an information extraction from a cardiological clinical study containing both clinical and gene expression data. The classification performance was evaluated by means of a cross validation study. Conclusions: The proposed classification system can be useful for clinicians in primary care to support their decision-making tasks with relevant information extracted from any available clinical study. It is especially suitable for analyzing high-dimensional data, e.g. gene expression measurements. (en)
Title
  • Selecting relevant information for medical decision support with application in cardiology
  • Selecting relevant information for medical decision support with application in cardiology (en)
skos:prefLabel
  • Selecting relevant information for medical decision support with application in cardiology
  • Selecting relevant information for medical decision support with application in cardiology (en)
skos:notation
  • RIV/00216208:11110/13:10194313!RIV14-MSM-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(1M06014), V
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 104516
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/13:10194313
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • gene expressions; high dimension; information extraction; web-service; Decision support system (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [BD4211ABE021]
http://linked.open...i/riv/nazevZdroje
  • Europaen Journal of Biomedical Informatics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 9
http://linked.open...iv/tvurceVysledku
  • Seidl, Libor
  • Slovák, Dalibor
  • Zvárová, Jana
  • Zvára, Karel
  • Kalina, Jan
  • Grünfeldová, Hana
issn
  • 1801-5603
number of pages
http://localhost/t...ganizacniJednotka
  • 11110
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