About: Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients     Goto   Sponge   NotDistinct   Permalink

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  • There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examine a hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain.
  • There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examine a hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain. (en)
Title
  • Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients
  • Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients (en)
skos:prefLabel
  • Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients
  • Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients (en)
skos:notation
  • RIV/00216208:11110/13:10193685!RIV14-GA0-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(ED1.1.00/02.0068), P(GAP407/12/1957), Z(MSM0021620849)
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  • 3
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http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 91469
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/13:10193685
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • sciatica pain; neuropathic pain; depressive symptoms; C-reactive protein (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [354912C93CBC]
http://linked.open...i/riv/nazevZdroje
  • International Journal of Neuroscience
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 123
http://linked.open...iv/tvurceVysledku
  • Bob, Petr
  • Uher, Tomáš
http://linked.open...ain/vavai/riv/wos
  • 000314898000009
http://linked.open...n/vavai/riv/zamer
issn
  • 0020-7454
number of pages
http://bibframe.org/vocab/doi
  • 10.3109/00207454.2012.746335
http://localhost/t...ganizacniJednotka
  • 11110
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