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rdfs:seeAlso
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Description
| - We demonstrated that JAK-2 is activated in a TGF-dependent manner in SSc. Considering the potent antifibrotic effects of JAK-2 inhibition, our study might have direct translational implications, because inhibitors of JAK-2 are currently being evaluated in clinical trials for myeloproliferative disorders and would also be available for evaluation in patients with SSc.
- We demonstrated that JAK-2 is activated in a TGF-dependent manner in SSc. Considering the potent antifibrotic effects of JAK-2 inhibition, our study might have direct translational implications, because inhibitors of JAK-2 are currently being evaluated in clinical trials for myeloproliferative disorders and would also be available for evaluation in patients with SSc. (en)
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Title
| - JAK-2 as a Novel Mediator of the Profibrotic Effects of Transforming Growth Factor beta in Systemic Sclerosis
- JAK-2 as a Novel Mediator of the Profibrotic Effects of Transforming Growth Factor beta in Systemic Sclerosis (en)
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skos:prefLabel
| - JAK-2 as a Novel Mediator of the Profibrotic Effects of Transforming Growth Factor beta in Systemic Sclerosis
- JAK-2 as a Novel Mediator of the Profibrotic Effects of Transforming Growth Factor beta in Systemic Sclerosis (en)
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skos:notation
| - RIV/00216208:11110/12:12731!RIV13-MSM-11110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11110/12:12731
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - systemic sclerosis; fibrosis; JAK-2; JAK-2 inhibitors (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Beyer, Christian
- Dees, Clara
- Horn, Angelika
- Tomčík, Michal
- Zerr, Pawel
- Distler, Alfiya
- Palumbo-Zerr, Katrin
- Zwerina, Jochen
- Gelse, Kolja
- Lang, Veronika
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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