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  • Our results contribute to the idea of oxytocin functioning as a cardiovascular hormone. Expression of OTR mRNA and immunohistochemical detection of OTR in all heart compartments indicate that oxytocin system plays an important regulatory role in the cardiovascular system both under basal and stress conditions. The distribution of oxytocin and its receptors in the heart, and in some cases their colocalization with nuclei are new findings, which can explain some controversial findings like quantitative discrepancy in expression of OTR mRNA and expression of OTR receptor protein. These findings require further studies and it can be expected that they will help to find target structures for therapeutic interventions.
  • Our results contribute to the idea of oxytocin functioning as a cardiovascular hormone. Expression of OTR mRNA and immunohistochemical detection of OTR in all heart compartments indicate that oxytocin system plays an important regulatory role in the cardiovascular system both under basal and stress conditions. The distribution of oxytocin and its receptors in the heart, and in some cases their colocalization with nuclei are new findings, which can explain some controversial findings like quantitative discrepancy in expression of OTR mRNA and expression of OTR receptor protein. These findings require further studies and it can be expected that they will help to find target structures for therapeutic interventions. (en)
Title
  • NEUROPEPTIDE OXYTOCIN IS ALSO SYNTHESIZED IN THE HEART UNDER BASAL AS WELL AS STRESS CONDITIONS AND FUNCTIONS AS A NEW CARDIOVASCULAR HORMONE
  • NEUROPEPTIDE OXYTOCIN IS ALSO SYNTHESIZED IN THE HEART UNDER BASAL AS WELL AS STRESS CONDITIONS AND FUNCTIONS AS A NEW CARDIOVASCULAR HORMONE (en)
skos:prefLabel
  • NEUROPEPTIDE OXYTOCIN IS ALSO SYNTHESIZED IN THE HEART UNDER BASAL AS WELL AS STRESS CONDITIONS AND FUNCTIONS AS A NEW CARDIOVASCULAR HORMONE
  • NEUROPEPTIDE OXYTOCIN IS ALSO SYNTHESIZED IN THE HEART UNDER BASAL AS WELL AS STRESS CONDITIONS AND FUNCTIONS AS A NEW CARDIOVASCULAR HORMONE (en)
skos:notation
  • RIV/00216208:11110/12:12386!RIV13-MSM-11110___
http://linked.open...avai/riv/aktivita
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  • S
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
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  • 153895
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/12:12386
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • NEUROPEPTIDE; OXYTOCIN; mRNA OXYTOCIN RECEPTOR; RT-PCR; IMMU8NOFLUORESCENT STUDY; HEART; STRESS (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [8CAE7161A9B1]
http://linked.open...v/mistoKonaniAkce
  • Hradec Králové, ČR
http://linked.open...i/riv/mistoVydani
  • Hradec Králové
http://linked.open...i/riv/nazevZdroje
  • 9th International Medical Postgraduate Conference New Frontiers in the Research of PhD Students
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Hynie, Sixtus
  • Klenerová, Věra
  • Škopek, Petr
  • Dzúr-Gejdošová, Mária
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • Charles University in Prague,Faculty of Medicine in Hradec Králové
https://schema.org/isbn
  • 978-80-260-3373-8
http://localhost/t...ganizacniJednotka
  • 11110
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