About: Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells

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About: Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1371/journal.pone.0024599
Description	The regulation of PrP(C) expression in differentiating MEL cells mimics the pattern detected on mouse erythroid precursors in vivo. Decrease of PrP(C) protein expression during MEL cell maturation is not regulated on transcriptional level. The efficient silencing of PrP(C) levels, despite not affecting MEL cell differentiation, enables created MEL lines to be used for studies of PrP(C) cellular function. The regulation of PrP(C) expression in differentiating MEL cells mimics the pattern detected on mouse erythroid precursors in vivo. Decrease of PrP(C) protein expression during MEL cell maturation is not regulated on transcriptional level. The efficient silencing of PrP(C) levels, despite not affecting MEL cell differentiation, enables created MEL lines to be used for studies of PrP(C) cellular function. (en)
Title	Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells (en)
skos:prefLabel	Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells (en)
skos:notation	RIV/00216208:11110/11:8961!RIV12-GA0-11110___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GA310/08/0878), S, Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Panigaj, Martin Holada, Karel Wildová, Marcela Glier, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	199028
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/11:8961
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	prion; hexamethylene bisacetamide; gene expression; blood cells; iron uptake; PRPC; dexamethasone (en)
http://linked.open.../riv/klicoveSlovo	gene expression PRPC blood cells dexamethasone hexamethylene bisacetamide iron uptake prion
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[51E9BBC18FBF]
http://linked.open...i/riv/nazevZdroje	PLoS One
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of cellular prion protein in erythroid differentiation: possible link to peripheral pathogenesis of prion diseases
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	6
http://linked.open...iv/tvurceVysledku	Holada, Karel Panigaj, Martin Glier, Hana Wildová, Marcela
http://linked.open...ain/vavai/riv/wos	000294686100051
http://linked.open...n/vavai/riv/zamer	Molekulární biologie a patologie buňky za normy a u vybraných klinicky závažných patologických procesů
issn	1932-6203
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	11110

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