About: Liver and muscle hemojuvelin are differently glycosylated     Goto   Sponge   NotDistinct   Permalink

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Description
  • Hemojuvelin (HJV) is one of essential components for expression of hepcidin, a hormone which regulates iron transport. HJV is mainly expressed in muscle and liver, and processing of HJV in both tissues is similar. However, hepcidin is expressed in liver but not in muscle and the role of the muscle HJV is yet to be established. Our preliminary analyses of mouse tissue HJV showed that the apparent molecular masses of HJV peptides are different in liver (50 kDa monomer and 35 and 20 kDa heterodimer fragments) and in muscle (55 kDa monomer and a 34 kDa possible large fragment of heterodimer). One possible explanation is glycosylation which could lead to difference in molecular mass.
  • Hemojuvelin (HJV) is one of essential components for expression of hepcidin, a hormone which regulates iron transport. HJV is mainly expressed in muscle and liver, and processing of HJV in both tissues is similar. However, hepcidin is expressed in liver but not in muscle and the role of the muscle HJV is yet to be established. Our preliminary analyses of mouse tissue HJV showed that the apparent molecular masses of HJV peptides are different in liver (50 kDa monomer and 35 and 20 kDa heterodimer fragments) and in muscle (55 kDa monomer and a 34 kDa possible large fragment of heterodimer). One possible explanation is glycosylation which could lead to difference in molecular mass. (en)
Title
  • Liver and muscle hemojuvelin are differently glycosylated
  • Liver and muscle hemojuvelin are differently glycosylated (en)
skos:prefLabel
  • Liver and muscle hemojuvelin are differently glycosylated
  • Liver and muscle hemojuvelin are differently glycosylated (en)
skos:notation
  • RIV/00216208:11110/11:8888!RIV12-MSM-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LC06044), Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika
  • art.n. 52
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 209759
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/11:8888
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • hemojuvelin; hepcidin (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [E7B9242D77F1]
http://linked.open...i/riv/nazevZdroje
  • BMC Biochemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 12
http://linked.open...iv/tvurceVysledku
  • Nečas, Emanuel
  • Krijt, Jan
  • Fujikura, Yuzo
http://linked.open...ain/vavai/riv/wos
  • 000295714500001
http://linked.open...n/vavai/riv/zamer
issn
  • 1471-2091
number of pages
http://localhost/t...ganizacniJednotka
  • 11110
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