About: Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer

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About: Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Intermediate products generated during the process of chromatin remodeling by RSC complex, the so-called remosomes, were identified by high-resolution cryo-electron microscopy and molecular biology methods. This remosome (remodeled nucleosome) is a metastable product of the first phase of the remodeling process. In contrast to original nucleosome, about 35 bp of DNA are associated with histone octamer, which results in creation of a DNA loop that dynamically moves around the perimeter of the octamer and allows thus access to originally inaccessible nucleosomal DNA. The measurement of the DNA accessibility by restricition enzymes showed that nucleosomal DNA was about 5x more accessible in comparison to its original state. Erratum in: Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):8041 Intermediate products generated during the process of chromatin remodeling by RSC complex, the so-called remosomes, were identified by high-resolution cryo-electron microscopy and molecular biology methods. This remosome (remodeled nucleosome) is a metastable product of the first phase of the remodeling process. In contrast to original nucleosome, about 35 bp of DNA are associated with histone octamer, which results in creation of a DNA loop that dynamically moves around the perimeter of the octamer and allows thus access to originally inaccessible nucleosomal DNA. The measurement of the DNA accessibility by restricition enzymes showed that nucleosomal DNA was about 5x more accessible in comparison to its original state. Erratum in: Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):8041 (en)
Title	Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer (en)
skos:prefLabel	Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer (en)
skos:notation	RIV/00216208:11110/10:6355!RIV11-GA0-11110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA304/05/2168), P(LC535), Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Bednár, Ján
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	284754
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/10:6355
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Intermediate; Mechanism; Nucleosome; Remodeling; Sliding (en)
http://linked.open.../riv/klicoveSlovo	Mechanism Intermediate Nucleosome Remodeling Sliding
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[FFDB227A059D]
http://linked.open...i/riv/nazevZdroje	Proceedings of the National Academy of Sciences of the USA
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Chromosome dynamics and organization during the cell cycle in normal and pathologic conditions Determination of the histone H5 globular domain position within the native nucleosome using cryo-electron microscopy and single particle reconstruction.
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	107
http://linked.open...iv/tvurceVysledku	Bednár, Ján Dimitrov, Stefan Faivre-Moskalenko, C. Montel, Fabien Shukla, Manu S. Travers, Andrew Angelov, Dimitar Syed, Sajad Hussain
http://linked.open...ain/vavai/riv/wos	000274296300026
http://linked.open...n/vavai/riv/zamer	Molekulární biologie a patologie buňky za normy a u vybraných klinicky závažných patologických procesů
issn	0027-8424
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	11110

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