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  • Gastric mucins play a major role in the protection of the gastrointestinal tract. The samples of gastric mucins of different origin obtained by an extraction of gastric mucosa with Tris-HCl buffer were separated using size exclusion chromatography on Sephadex G-100. While samples of rat gastric mucins are characterized by the presence of only high-molecular weight fraction of glycoproteins, fragmented mucin components in non-denaturated samples were observed in canine and human gastric mucins. Differences in the fragmentation pattern were observed in patients with ulcer diseases and gastric cancer.
  • Gastric mucins play a major role in the protection of the gastrointestinal tract. The samples of gastric mucins of different origin obtained by an extraction of gastric mucosa with Tris-HCl buffer were separated using size exclusion chromatography on Sephadex G-100. While samples of rat gastric mucins are characterized by the presence of only high-molecular weight fraction of glycoproteins, fragmented mucin components in non-denaturated samples were observed in canine and human gastric mucins. Differences in the fragmentation pattern were observed in patients with ulcer diseases and gastric cancer. (en)
Title
  • Size exclusion chromatography as a tool for evaluation of fragmentation pattern of gastric mucins under non-degrading conditions
  • Size exclusion chromatography as a tool for evaluation of fragmentation pattern of gastric mucins under non-degrading conditions (en)
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  • Size exclusion chromatography as a tool for evaluation of fragmentation pattern of gastric mucins under non-degrading conditions
  • Size exclusion chromatography as a tool for evaluation of fragmentation pattern of gastric mucins under non-degrading conditions (en)
skos:notation
  • RIV/00216208:11110/10:6261!RIV11-GA0-11110___
http://linked.open...avai/riv/aktivita
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  • I, P(GA203/09/0857), P(LC06044), Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
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  • 287634
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  • RIV/00216208:11110/10:6261
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  • gastric mucins; glycoproteins; chromatography (en)
http://linked.open.../riv/klicoveSlovo
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  • CZ - Česká republika
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  • [FFB411A17FD1]
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  • Prague Medical Report
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  • 111
http://linked.open...iv/tvurceVysledku
  • Tichá, Marie
  • Kučerová, Zdenka
  • Muselová, Hana
  • Miarková, Eva
http://linked.open...n/vavai/riv/zamer
issn
  • 1214-6994
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http://localhost/t...ganizacniJednotka
  • 11110
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