About: Whole brain radiotherapy: consequence for personalized medicine

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1016/j.rpor.2013.03.002
Description	Several studies focusing on brain irradiation are in progress. Reflecting updates of relevant outcomes in palliative treatment of patients suffering from brain metastases, the primary objective of these studies is the evaluation of neurocognitive function and quality of life. Improvements of technology in radiation oncology allows us to spare the hippocampal region while appropriately irradiating other parts of brain tissue. Irradiation of the hippocampus region is likely to lead to manifestations of adverse events with a subsequent impact on patient’s quality of life, which is in fact an improper approach in palliative medicine. Ongoing studies evaluate results of hippocampus avoiding radiotherapy compared to standard whole brain radiotherapy. Incorporation of neurocognitive function assessment may result in the confirmation of superiority of sparing the region of hippocampus and thus change current style of providing brain irradiation. Several studies focusing on brain irradiation are in progress. Reflecting updates of relevant outcomes in palliative treatment of patients suffering from brain metastases, the primary objective of these studies is the evaluation of neurocognitive function and quality of life. Improvements of technology in radiation oncology allows us to spare the hippocampal region while appropriately irradiating other parts of brain tissue. Irradiation of the hippocampus region is likely to lead to manifestations of adverse events with a subsequent impact on patient’s quality of life, which is in fact an improper approach in palliative medicine. Ongoing studies evaluate results of hippocampus avoiding radiotherapy compared to standard whole brain radiotherapy. Incorporation of neurocognitive function assessment may result in the confirmation of superiority of sparing the region of hippocampus and thus change current style of providing brain irradiation. (en)
Title	Whole brain radiotherapy: consequence for personalized medicine Whole brain radiotherapy: consequence for personalized medicine (en)
skos:prefLabel	Whole brain radiotherapy: consequence for personalized medicine Whole brain radiotherapy: consequence for personalized medicine (en)
skos:notation	RIV/00209805:_____/13:#0000437!RIV14-MZ0-00209805
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED2.1.00/03.0101), P(NT14120), P(NT14600)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Šlampa, Pavel Pospíšil, Petr Doleželová, Hana Kazda, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykův onkologický ústav
http://linked.open...dnocenehoVysledku	117339
http://linked.open...ai/riv/idVysledku	RIV/00209805:_____/13:#0000437
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	whole brain radiotherapy; brain metastases; brain metastases; decision-making; personalized medicine (en)
http://linked.open.../riv/klicoveSlovo	decision-making brain metastases whole brain radiotherapy personalized medicine
http://linked.open...odStatuVydavatele	PL - Polská republika
http://linked.open...ontrolniKodProRIV	[7A7C4AA44EF2]
http://linked.open...i/riv/nazevZdroje	Reports of Practical Oncology and Radiotherapy
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Regional Centre for Applied Molecular Oncology (RECAMO) Using advanced MRI techniques for diagnosis of high-grade glioma relapse after complex oncology treatment Correlation of MR spectroscopy image of hippocampus region and impairment of cognitive functions in patients after brain irradiation
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Šlampa, Pavel Pospíšil, Petr Doleželová, Hana Kazda, Tomáš
issn	1507-1367
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.rpor.2013.03.002

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