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  • It has been reported that central administration of agouti-related peptide (AgRP) might have protective effect against cachexia development in tumor-bearing mice. In this study, we determined whether the disease-free endometrial cancer survivors present with different plasma AgRP levels than controls and whether there was an association with the duration of the disease- free interval. We observed significant differences in AgRP levels between endometrial cancer survivors and tcontrol subjects. Disease-free endometrial cancer survivors who did not develop cachexia during their treatment as well as post-treatreatment period present with significantly higher AgRP levels independently on their BMI and menopausal status which could be indicative of the protective effect of circulating AgRP against cachexia development in endometrial cancer.
  • It has been reported that central administration of agouti-related peptide (AgRP) might have protective effect against cachexia development in tumor-bearing mice. In this study, we determined whether the disease-free endometrial cancer survivors present with different plasma AgRP levels than controls and whether there was an association with the duration of the disease- free interval. We observed significant differences in AgRP levels between endometrial cancer survivors and tcontrol subjects. Disease-free endometrial cancer survivors who did not develop cachexia during their treatment as well as post-treatreatment period present with significantly higher AgRP levels independently on their BMI and menopausal status which could be indicative of the protective effect of circulating AgRP against cachexia development in endometrial cancer. (en)
Title
  • Circulating levels of agouti-related peptide in endometrial cancer survivors
  • Circulating levels of agouti-related peptide in endometrial cancer survivors (en)
skos:prefLabel
  • Circulating levels of agouti-related peptide in endometrial cancer survivors
  • Circulating levels of agouti-related peptide in endometrial cancer survivors (en)
skos:notation
  • RIV/00209805:_____/11:#0000156!RIV12-MSM-00209805
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(ED2.1.00/03.0101), Z(MZ0MOU2005)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
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  • 190446
http://linked.open...ai/riv/idVysledku
  • RIV/00209805:_____/11:#0000156
http://linked.open...riv/jazykVysledku
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  • agouti-related peptide; cachexia; cancer; cancer survivors (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CA - Kanada
http://linked.open...ontrolniKodProRIV
  • [ECB76EEF176F]
http://linked.open...i/riv/nazevZdroje
  • World journal of oncology
http://linked.open...in/vavai/riv/obor
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 2
http://linked.open...iv/tvurceVysledku
  • Bienertová-Vašků, Julie
  • Chovanec, Josef
  • Dostálová, Zuzana
  • Valík, Dalibor
http://linked.open...n/vavai/riv/zamer
issn
  • 1920-4531
number of pages
http://bibframe.org/vocab/doi
  • 10.4021/wjon385w
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