About: Surface-enhanced laser desorption ionization/time-of-flight (SELDI-TOF) mass spectrometry (MS) as a phenotypic method for rapid identification of antibiotic resistance     Goto   Sponge   NotDistinct   Permalink

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Description
  • Based on experiments with 10 defined strains of Escherichia coli, we present a new method for bacterial phenotyping using SELDI-TOF mass spectrometry. Changes in bacterial protein profiles in the context of the time of cultivation and the antibiotic environment were minimal. Proteom subprofiling may further distinguish between strains with specific susceptibility to antimicrobials. Mass spec-based methods may become common in the future of bacterial pathogen identification in clinical microbiology diagnostics.
  • Based on experiments with 10 defined strains of Escherichia coli, we present a new method for bacterial phenotyping using SELDI-TOF mass spectrometry. Changes in bacterial protein profiles in the context of the time of cultivation and the antibiotic environment were minimal. Proteom subprofiling may further distinguish between strains with specific susceptibility to antimicrobials. Mass spec-based methods may become common in the future of bacterial pathogen identification in clinical microbiology diagnostics. (en)
Title
  • Surface-enhanced laser desorption ionization/time-of-flight (SELDI-TOF) mass spectrometry (MS) as a phenotypic method for rapid identification of antibiotic resistance
  • Surface-enhanced laser desorption ionization/time-of-flight (SELDI-TOF) mass spectrometry (MS) as a phenotypic method for rapid identification of antibiotic resistance (en)
skos:prefLabel
  • Surface-enhanced laser desorption ionization/time-of-flight (SELDI-TOF) mass spectrometry (MS) as a phenotypic method for rapid identification of antibiotic resistance
  • Surface-enhanced laser desorption ionization/time-of-flight (SELDI-TOF) mass spectrometry (MS) as a phenotypic method for rapid identification of antibiotic resistance (en)
skos:notation
  • RIV/00209805:_____/11:#0000152!RIV12-MSM-00209805
http://linked.open...avai/riv/aktivita
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  • I, P(ED2.1.00/03.0101), P(GA203/08/1680), P(GPP502/10/P083)
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  • 6
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  • 233510
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  • RIV/00209805:_____/11:#0000152
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  • SELDI-TOF MS; phenotyping; bacteria identification (en)
http://linked.open.../riv/klicoveSlovo
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [8DD7DC652200]
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  • Anaerobe
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  • 17
http://linked.open...iv/tvurceVysledku
  • Dubská, Lenka
  • Valík, Dalibor
  • Pilátová, Kateřina
http://linked.open...ain/vavai/riv/wos
  • 000299982800048
issn
  • 1075-9964
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.anaerobe.2011.05.008
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