About: Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial

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About: Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The purpose of this study was to test, whether the late phase of remote ischaemic preconditioning (L-RIPC) improves myocardial protection in coronary artery bypass grafting (CABG) with cold-crystalloid cardioplegia and whether preoperative tramadol modifies myocardial ischaemia-reperfusion injury using the same group of patients in a single-blinded randomized controlled study. One hundred and one adult patients were randomly assigned to either the L-RIPC, control or tramadol group. We found that L-RIPC can reduce injury beyond the myocardial protection provided by cold-crystalloid cardioplegia, and tramadol worsened myocardial injury after CABG. Expressions of iNOS were increased in the control (significantly) and L-RIPC groups and dampened in the tramadol group. The purpose of this study was to test, whether the late phase of remote ischaemic preconditioning (L-RIPC) improves myocardial protection in coronary artery bypass grafting (CABG) with cold-crystalloid cardioplegia and whether preoperative tramadol modifies myocardial ischaemia-reperfusion injury using the same group of patients in a single-blinded randomized controlled study. One hundred and one adult patients were randomly assigned to either the L-RIPC, control or tramadol group. We found that L-RIPC can reduce injury beyond the myocardial protection provided by cold-crystalloid cardioplegia, and tramadol worsened myocardial injury after CABG. Expressions of iNOS were increased in the control (significantly) and L-RIPC groups and dampened in the tramadol group. (en)
Title	Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial (en)
skos:prefLabel	Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial (en)
skos:notation	RIV/00209775:_____/10:#0000129!RIV11-MZ0-00209775
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NR9194)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Adámek, Petr Grodecká, Lucie Piler, Pavel Freiberger, Tomáš Bedáňová, Helena Wagner, Robert
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Centrum kardiovaskulární a transplantační chirurgie
http://linked.open...dnocenehoVysledku	273341
http://linked.open...ai/riv/idVysledku	RIV/00209775:_____/10:#0000129
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	myocardial protection; ischaemic preconditioning; Troponini; inducible nitric oxide synthase; endothelial nitric oxyde synthases (en)
http://linked.open.../riv/klicoveSlovo	Troponini endothelial nitric oxyde synthases ischaemic preconditioning myocardial protection inducible nitric oxide synthase
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[9181C24EC369]
http://linked.open...i/riv/nazevZdroje	Interactive cardiovascular and thoracic surgery
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Regulation of the Nitric Oxide during Cardiac operation with Cardiopulmonary Bypass
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Adámek, Petr Freiberger, Tomáš Bedáňová, Helena Wagner, Robert Piler, Pavel Grodecká, Lucie
issn	1569-9293
number of pages	5 (xsd:int)

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