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Description
| - The purpose of this study was to test, whether the late phase of remote ischaemic preconditioning (L-RIPC) improves myocardial protection in coronary artery bypass grafting (CABG) with cold-crystalloid cardioplegia and whether preoperative tramadol modifies myocardial ischaemia-reperfusion injury using the same group of patients in a single-blinded randomized controlled study. One hundred and one adult patients were randomly assigned to either the L-RIPC, control or tramadol group. We found that L-RIPC can reduce injury beyond the myocardial protection provided by cold-crystalloid cardioplegia, and tramadol worsened myocardial injury after CABG. Expressions of iNOS were increased in the control (significantly) and L-RIPC groups and dampened in the tramadol group.
- The purpose of this study was to test, whether the late phase of remote ischaemic preconditioning (L-RIPC) improves myocardial protection in coronary artery bypass grafting (CABG) with cold-crystalloid cardioplegia and whether preoperative tramadol modifies myocardial ischaemia-reperfusion injury using the same group of patients in a single-blinded randomized controlled study. One hundred and one adult patients were randomly assigned to either the L-RIPC, control or tramadol group. We found that L-RIPC can reduce injury beyond the myocardial protection provided by cold-crystalloid cardioplegia, and tramadol worsened myocardial injury after CABG. Expressions of iNOS were increased in the control (significantly) and L-RIPC groups and dampened in the tramadol group. (en)
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Title
| - Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial
- Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial (en)
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skos:prefLabel
| - Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial
- Myocardial injury is decreased by late remote ischaemic preconditioning and aggravated by tramadol in patients undergoing cardicac surgery: a randomised controlled trial (en)
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skos:notation
| - RIV/00209775:_____/10:#0000129!RIV11-MZ0-00209775
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00209775:_____/10:#0000129
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - myocardial protection; ischaemic preconditioning; Troponini; inducible nitric oxide synthase; endothelial nitric oxyde synthases (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Interactive cardiovascular and thoracic surgery
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Adámek, Petr
- Freiberger, Tomáš
- Bedáňová, Helena
- Wagner, Robert
- Piler, Pavel
- Grodecká, Lucie
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issn
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number of pages
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