About: Prognostic Significance of Serum Neopterin in Patients with Esophageal Carcinoma

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.pteridines.sk/bild/2012/160/2012-01-03-melichar-folinat.pdf
Description	Increased concentrations of neopterin have been described in patients with tumors of different primary locations, but reports on neopterin in patients with carcinoma of the esophagus are still very limited. We have studied serum neopterin in 45 patients with histologically verified carcinoma of the esophagus. Serum neopterin was determined with radioimmunoassay. Neopterin concentrations above median (6.5 nmol/L) were associated with inferior prognosis in patients with early esophageal carcinoma. In multivariate analysis, tumor stage and serum neopterin were predictors of survival in patients without distant metastases. In conclusion, serum neopterin is an independent prognostic factor in patients with esophageal carcinoma. Increased concentrations of neopterin have been described in patients with tumors of different primary locations, but reports on neopterin in patients with carcinoma of the esophagus are still very limited. We have studied serum neopterin in 45 patients with histologically verified carcinoma of the esophagus. Serum neopterin was determined with radioimmunoassay. Neopterin concentrations above median (6.5 nmol/L) were associated with inferior prognosis in patients with early esophageal carcinoma. In multivariate analysis, tumor stage and serum neopterin were predictors of survival in patients without distant metastases. In conclusion, serum neopterin is an independent prognostic factor in patients with esophageal carcinoma. (en)
Title	Prognostic Significance of Serum Neopterin in Patients with Esophageal Carcinoma Prognostic Significance of Serum Neopterin in Patients with Esophageal Carcinoma (en)
skos:prefLabel	Prognostic Significance of Serum Neopterin in Patients with Esophageal Carcinoma Prognostic Significance of Serum Neopterin in Patients with Esophageal Carcinoma (en)
skos:notation	RIV/00179906:_____/12:10124675!RIV13-MZ0-00179906
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Malířová, Eva Krčmová, Lenka Solichová, Dagmar Melichar, Bohuslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	162598
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/12:10124675
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	prognosis; neopterin; esophageal carcinoma (en)
http://linked.open.../riv/klicoveSlovo	esophageal carcinoma neopterin prognosis
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[C72162CB46E1]
http://linked.open...i/riv/nazevZdroje	Pteridines
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	23
http://linked.open...iv/tvurceVysledku	Krčmová, Lenka Melichar, Bohuslav Neoral, Čestmír Solichová, Dagmar Zezulová, Michaela Malířová, Eva Cincibuch, Jan Cwiertka, Karel Kalabová, Hana Prochazková-Študentová, Hana
http://linked.open...ain/vavai/riv/wos	000307700500004
http://linked.open...n/vavai/riv/zamer	Modulation of signalling and regulatory pathways in normal and cancer cells
issn	0933-4807
number of pages	5 (xsd:int)

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