About: Utilization of cone-beam CT for offline evaluation of target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment     Goto   Sponge   NotDistinct   Permalink

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Description
  • To assess target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment and to assess possibility of safety margin reduction. Implementation of IGRT should influence safety margins. Utilization of conebeam CT provides current 3D anatomic information directly in irradiation position. Such information enables reconstruction of the actual dose distribution. In 12 % of reconstructed plans the prostate coverage was not sufficient. The prostate underdosage was observed in 5 patients. Coverage of seminal vesicles was not satisfactory in 3 % of plans. Most of the target underdosage corresponded to excessive rectal of bladder filling. Evaluation of alternative plans assuming a smaller 7 mm margin revealed 22 % and 11 % of plans where prostate and seminal vesicles coverage, respectively, was compromised. These were distributed over 8 and 7 patients, respectively. Sufficient dose coverage of target volumes was not achieved for all patients. Reducing of safety margin is not acceptable. Initial rectal and bladder volumes cannot be considered representative for subsequent treatment.
  • To assess target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment and to assess possibility of safety margin reduction. Implementation of IGRT should influence safety margins. Utilization of conebeam CT provides current 3D anatomic information directly in irradiation position. Such information enables reconstruction of the actual dose distribution. In 12 % of reconstructed plans the prostate coverage was not sufficient. The prostate underdosage was observed in 5 patients. Coverage of seminal vesicles was not satisfactory in 3 % of plans. Most of the target underdosage corresponded to excessive rectal of bladder filling. Evaluation of alternative plans assuming a smaller 7 mm margin revealed 22 % and 11 % of plans where prostate and seminal vesicles coverage, respectively, was compromised. These were distributed over 8 and 7 patients, respectively. Sufficient dose coverage of target volumes was not achieved for all patients. Reducing of safety margin is not acceptable. Initial rectal and bladder volumes cannot be considered representative for subsequent treatment. (en)
Title
  • Utilization of cone-beam CT for offline evaluation of target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment
  • Utilization of cone-beam CT for offline evaluation of target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment (en)
skos:prefLabel
  • Utilization of cone-beam CT for offline evaluation of target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment
  • Utilization of cone-beam CT for offline evaluation of target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment (en)
skos:notation
  • RIV/00179906:_____/12:10123857!RIV13-MZ0-00179906
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, S
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 176652
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  • RIV/00179906:_____/12:10123857
http://linked.open...riv/jazykVysledku
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  • dose-volume histogram; dose reconstruction; cone-beam computed tomography; image-guided radiotherapy; prostate (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • PL - Polská republika
http://linked.open...ontrolniKodProRIV
  • [84A432617911]
http://linked.open...i/riv/nazevZdroje
  • Reports of Practical Oncology and Radiotherapy
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 17
http://linked.open...iv/tvurceVysledku
  • Petera, Jiří
  • Vošmik, Milan
  • Hanuš, Josef
  • Hodek, Miroslav
  • Kašaová, Linda
  • Paluska, Petr
  • Jansa, Jan
  • Zouhar, Milan
  • Šefrová, Jana
  • Grepl, Jakub
  • Rousková, Lucie
issn
  • 1507-1367
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.rpor.2012.03.003
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