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  • AIM: To study possible decrease in prevalence of Helicobacter pylori (Hp) infection in the Czech Republic within a 10-year period. METHODS: A total of 22 centres entered the study. The catchment areas of these centres covered cities and towns with more than 20,000 inhabitants, smaller towns (LESS-THAN OR EQUAL TO 20,000 inhabitants) with surrounding villages and rural areas, and were spread over the whole country, corresponding well to the geographical distribution of the Czech population. A total of 1,837 subjects (aged 5-98 years) took part in the study, randomly selected out of 38,147 people from the general population. Hp infection was investigated by means of a 13C-urea breath test. Breath samples in duplicates were analysed using isotope ratio mass spectrometry. The cut-off point was 3.5. Social and demographic characteristics were based on data from self-completed questionnaires. RESULTS: Results of 13C-urea breath test for Hp status were obtained for 99.4% (1,826/1,837) of subjects. The overall prevalence of Hp infection was 23.5% (430/1826), and 4.8% (20/420) in children below the age of 15. There was no difference in prevalence between males (24.3%; 208/857) and females (22.9%; 222/969; p=0.494). Hp infection was associated with higher age and lower education. The current prevalence of Hp in 2011 was significantly lower compared to the prevalence of identical geographical areas in 2001 (23.5% vs 41.7%; p<0.001). CONCLUSION: The overall prevalence of Hp infection in the general population has fallen substantially in the Czech Republic over the past 10 years.
  • AIM: To study possible decrease in prevalence of Helicobacter pylori (Hp) infection in the Czech Republic within a 10-year period. METHODS: A total of 22 centres entered the study. The catchment areas of these centres covered cities and towns with more than 20,000 inhabitants, smaller towns (LESS-THAN OR EQUAL TO 20,000 inhabitants) with surrounding villages and rural areas, and were spread over the whole country, corresponding well to the geographical distribution of the Czech population. A total of 1,837 subjects (aged 5-98 years) took part in the study, randomly selected out of 38,147 people from the general population. Hp infection was investigated by means of a 13C-urea breath test. Breath samples in duplicates were analysed using isotope ratio mass spectrometry. The cut-off point was 3.5. Social and demographic characteristics were based on data from self-completed questionnaires. RESULTS: Results of 13C-urea breath test for Hp status were obtained for 99.4% (1,826/1,837) of subjects. The overall prevalence of Hp infection was 23.5% (430/1826), and 4.8% (20/420) in children below the age of 15. There was no difference in prevalence between males (24.3%; 208/857) and females (22.9%; 222/969; p=0.494). Hp infection was associated with higher age and lower education. The current prevalence of Hp in 2011 was significantly lower compared to the prevalence of identical geographical areas in 2001 (23.5% vs 41.7%; p<0.001). CONCLUSION: The overall prevalence of Hp infection in the general population has fallen substantially in the Czech Republic over the past 10 years. (en)
Title
  • Significant decrease in prevalence of Helicobacter pylori in the Czech Republic
  • Significant decrease in prevalence of Helicobacter pylori in the Czech Republic (en)
skos:prefLabel
  • Significant decrease in prevalence of Helicobacter pylori in the Czech Republic
  • Significant decrease in prevalence of Helicobacter pylori in the Czech Republic (en)
skos:notation
  • RIV/00179906:_____/12:10123816!RIV13-MZ0-00179906
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, V
http://linked.open...iv/cisloPeriodika
  • 32
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 167829
http://linked.open...ai/riv/idVysledku
  • RIV/00179906:_____/12:10123816
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Decline of prevalence; 13C-urea breath test; Czech Republic; Helicobacter pylori; Epidemiology (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CN - Čínská lidová republika
http://linked.open...ontrolniKodProRIV
  • [C6CD2841DDCD]
http://linked.open...i/riv/nazevZdroje
  • World Journal of Gastroenterology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 18
http://linked.open...iv/tvurceVysledku
  • Bureš, Jan
  • Kopáčová, Marcela
  • Rejchrt, Stanislav
  • Seifert, Bohumil
  • Tachecí, Ilja
  • Voříšek, Viktor
  • Škodová Fendrichová, Miluška
  • Douda, Tomáš
  • Špirková, Jana
  • Koupil, Ilona
  • Král, Norbert
http://linked.open...ain/vavai/riv/wos
  • 000308779500021
issn
  • 1007-9327
number of pages
http://bibframe.org/vocab/doi
  • 10.3748/wjg.v18.i32.4412
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