About: Colonization of Recipient Tissues with Transplanted Murine Bone Marrow Cells

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/article/pii/S1473050211002114
Description	The whole body irradiation of mice by lethal doses represents a standard model for elimination of endogenous hemopoiesis and demonstration of efficacy of transplantation heterogenous population bone marrow cells - hematopoietic stem cells (HSCs). Transplantation of bone marrow cells or sorted lin-/CD117+resulted in hematopoietic recovery and survival of irradiated mice as shown by determination of CFU-GM numbers in bone marrow of transplanted animals as we described previously (Filip e al.Transf Apher Sci 41, 2009, 183-190). Bone marrow-derived cells after i.v. administration do not necessarily engraft back to the bone marrow. To trace distribution of grafted cells in the recipient organism, we utilized transgenic mice as donors whose cells are tagged to endogenous vectors. The whole body irradiation of mice by lethal doses represents a standard model for elimination of endogenous hemopoiesis and demonstration of efficacy of transplantation heterogenous population bone marrow cells - hematopoietic stem cells (HSCs). Transplantation of bone marrow cells or sorted lin-/CD117+resulted in hematopoietic recovery and survival of irradiated mice as shown by determination of CFU-GM numbers in bone marrow of transplanted animals as we described previously (Filip e al.Transf Apher Sci 41, 2009, 183-190). Bone marrow-derived cells after i.v. administration do not necessarily engraft back to the bone marrow. To trace distribution of grafted cells in the recipient organism, we utilized transgenic mice as donors whose cells are tagged to endogenous vectors. (en)
Title	Colonization of Recipient Tissues with Transplanted Murine Bone Marrow Cells Colonization of Recipient Tissues with Transplanted Murine Bone Marrow Cells (en)
skos:prefLabel	Colonization of Recipient Tissues with Transplanted Murine Bone Marrow Cells Colonization of Recipient Tissues with Transplanted Murine Bone Marrow Cells (en)
skos:notation	RIV/00179906:_____/12:10105024!RIV13-MZ0-00179906
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GA304/08/0329)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Bláha, Milan Filip, Stanislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	127646
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/12:10105024
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Homing; Bone marrow; Transplantation; Hematopoietic stem cells (en)
http://linked.open.../riv/klicoveSlovo	Bone marrow Homing Hematopoietic stem cells Transplantation
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[698CB4E99BA5]
http://linked.open...i/riv/nazevZdroje	Transfusion and Apheresis Science
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of factors in a tissue microenvironment that influence the process of skeletal muscle reparation.
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	46
http://linked.open...iv/tvurceVysledku	Bláha, Milan Filip, Stanislav Mičuda, Stanislav Mokrý, Jaroslav Vávrová, Jiřina Čížková, Dana
http://linked.open...ain/vavai/riv/wos	000301812200025
issn	1473-0502
number of pages	3 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.transci.2011.11.006

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