About: Tamoxifen/Norfloxacin interaction leading to QT interval prolongation in a female patient with extracranial meningioma

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About: Tamoxifen/Norfloxacin interaction leading to QT interval prolongation in a female patient with extracranial meningioma Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.bmj.sk/2011/11206-10.pdf
Description	The autors report on a case of tamoxifen/norfloxacin interaction leading to QT interval prolongation in an 83-year-old female patient with extracranial meningioma treated with radiation and hormonal therapy (with Tamoxifen). This case report highlights the potential risk of tamoxifen causing depression of electrical impulse in sinoatrial node, leading to symptomatic sinus bradycardia with prolonged QT interval. At the same time it indicates the need to be on the look out for drug interactions (in our case between tamoxifen and norfloxacin), as well as to be aware of other drugs possibly inducing QT interval prolongation) The autors report on a case of tamoxifen/norfloxacin interaction leading to QT interval prolongation in an 83-year-old female patient with extracranial meningioma treated with radiation and hormonal therapy (with Tamoxifen). This case report highlights the potential risk of tamoxifen causing depression of electrical impulse in sinoatrial node, leading to symptomatic sinus bradycardia with prolonged QT interval. At the same time it indicates the need to be on the look out for drug interactions (in our case between tamoxifen and norfloxacin), as well as to be aware of other drugs possibly inducing QT interval prolongation) (en)
Title	Tamoxifen/Norfloxacin interaction leading to QT interval prolongation in a female patient with extracranial meningioma Tamoxifen/Norfloxacin interaction leading to QT interval prolongation in a female patient with extracranial meningioma (en)
skos:prefLabel	Tamoxifen/Norfloxacin interaction leading to QT interval prolongation in a female patient with extracranial meningioma Tamoxifen/Norfloxacin interaction leading to QT interval prolongation in a female patient with extracranial meningioma (en)
skos:notation	RIV/00179906:_____/11:10106326!RIV12-MZ0-00179906
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Priester, Peter Slováček, Ladislav Kopecký, Jindřich Petera, Jiří Slánská, Iva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	234193
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/11:10106326
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	meningioma; Q-Tc interval; drug-interaction; norfloxacin; tamoxifen (en)
http://linked.open.../riv/klicoveSlovo	Q-Tc interval drug-interaction meningioma norfloxacin tamoxifen
http://linked.open...odStatuVydavatele	SK - Slovenská republika
http://linked.open...ontrolniKodProRIV	[60E9CCA63350]
http://linked.open...i/riv/nazevZdroje	Bratislavske Lekarske Listy
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	112
http://linked.open...iv/tvurceVysledku	Kopecký, Jindřich Petera, Jiří Priester, Peter Slováček, Ladislav Slánská, Iva
http://linked.open...ain/vavai/riv/wos	000291378700010
http://linked.open...n/vavai/riv/zamer	Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	0006-9248
number of pages	2 (xsd:int)

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