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| rdf:type
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| rdfs:seeAlso
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| Description
| - Chronic sclerosing sialadenitis (CSS) has been recently proposed to be member of IgG4-related disease in Japanese and American series. The aim of our study was to validate these results in a cohort of European patients. Our CSS-series includes 4 females and 2 males, aged 32-76 years, all presenting with unilateral swelling of submandibular gland. Microscopically, all CSS-cases showed similar morphology - preservation of lobular architecture accentuated by cellular fibrous bands, dense lymphoplasmacytic inflammation and varied acinar atrophy. Ductal lymphocytes were detected in 3 cases. In 5 cases, the presence of intraductal secretory material accompanied by parenchymal neutrophils was observed. Obliterative phlebitis was seen in 3 cases. The inflammatory infiltrate was composed of T- and B-lymphocytes and polyclonal plasma cells. Median number of IgG-positive plasma cells per 1 HPF was 157; median number of IgG4-positive plasma cells per 1 HPF was 133. Median value of IgG4/IgG ratio was 0.84. Ours is the first European series to prove that CSS belongs to the family of IgG4-related disease. Unlike prior studies, we found in CSS rarely described ductal lymphocytes and parenchymal neutrophils. CSS displays consistent morphology, with increased numbers of IgG4-positive plasma cells and should be regarded as member of IgG4-related disease group.
- Chronic sclerosing sialadenitis (CSS) has been recently proposed to be member of IgG4-related disease in Japanese and American series. The aim of our study was to validate these results in a cohort of European patients. Our CSS-series includes 4 females and 2 males, aged 32-76 years, all presenting with unilateral swelling of submandibular gland. Microscopically, all CSS-cases showed similar morphology - preservation of lobular architecture accentuated by cellular fibrous bands, dense lymphoplasmacytic inflammation and varied acinar atrophy. Ductal lymphocytes were detected in 3 cases. In 5 cases, the presence of intraductal secretory material accompanied by parenchymal neutrophils was observed. Obliterative phlebitis was seen in 3 cases. The inflammatory infiltrate was composed of T- and B-lymphocytes and polyclonal plasma cells. Median number of IgG-positive plasma cells per 1 HPF was 157; median number of IgG4-positive plasma cells per 1 HPF was 133. Median value of IgG4/IgG ratio was 0.84. Ours is the first European series to prove that CSS belongs to the family of IgG4-related disease. Unlike prior studies, we found in CSS rarely described ductal lymphocytes and parenchymal neutrophils. CSS displays consistent morphology, with increased numbers of IgG4-positive plasma cells and should be regarded as member of IgG4-related disease group. (en)
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| Title
| - Chronic sclerosing sialadenitis as one of the immunoglobulin G4-related diseases: a clinicopathological study of six cases from Central Europe
- Chronic sclerosing sialadenitis as one of the immunoglobulin G4-related diseases: a clinicopathological study of six cases from Central Europe (en)
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| skos:prefLabel
| - Chronic sclerosing sialadenitis as one of the immunoglobulin G4-related diseases: a clinicopathological study of six cases from Central Europe
- Chronic sclerosing sialadenitis as one of the immunoglobulin G4-related diseases: a clinicopathological study of six cases from Central Europe (en)
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| skos:notation
| - RIV/00179906:_____/11:10106020!RIV12-MZ0-00179906
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00179906:_____/11:10106020
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - salivary gland; Küttner tumour; IgG4 plasma cells; chronic sclerosing sialadenitis (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Doležalová, Helena
- Laco, Jan
- Mottl, Radovan
- Ryška, Aleš
- Tuček, Luboš
- Čelakovský, Petr
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| http://linked.open...ain/vavai/riv/wos
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://bibframe.org/vocab/doi
| - 10.1111/j.1365-2559.2011.03833.x
|
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