About: A Phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema     Goto   Sponge   NotDistinct   Permalink

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Description
  • To confirm the safety and compare the efficacy of intravitreal pegaptanib sodium 0,3mg versus sham injection in subject with diabetic macular edema (DME). 36,8% subjects from the pegaptanib group versus 19,7% subjects from the sham group experienced a VA improvement of 10 letters at week 54. At week 102, pegaptanib treated subjects gained, on average, 6,1 letters versus 1,3 letters for sham (P0,01). These findings indicate that intravitreal pegaptanib is effective in the traetment of DME and has positive safety profile.
  • To confirm the safety and compare the efficacy of intravitreal pegaptanib sodium 0,3mg versus sham injection in subject with diabetic macular edema (DME). 36,8% subjects from the pegaptanib group versus 19,7% subjects from the sham group experienced a VA improvement of 10 letters at week 54. At week 102, pegaptanib treated subjects gained, on average, 6,1 letters versus 1,3 letters for sham (P0,01). These findings indicate that intravitreal pegaptanib is effective in the traetment of DME and has positive safety profile. (en)
Title
  • A Phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema
  • A Phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema (en)
skos:prefLabel
  • A Phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema
  • A Phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema (en)
skos:notation
  • RIV/00179906:_____/11:10105563!RIV12-MZ0-00179906
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, N
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 184053
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  • RIV/00179906:_____/11:10105563
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  • diabetic macular edema; pegaptanib sodium (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [F6EABF2F6247]
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  • Ophthalmology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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  • 118
http://linked.open...iv/tvurceVysledku
  • Dombi, T.
  • Dusová, Jaroslava
  • Ice, K. S.
  • Loftus, J.
  • Macugen 1013, Study Group
  • Sultan, M. B.
  • Zhou, D.
http://linked.open...ain/vavai/riv/wos
  • 000291152700016
issn
  • 0161-6420
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.ophtha.2011.02.045
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