About: Severe hypocholesterolemia in surgical patients, sepsis, and critical illness

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About: Severe hypocholesterolemia in surgical patients, sepsis, and critical illness Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	After surgery, in sepsis and various critical illnesses, factors such as severity of the acute phase response, liver dysfunction, and hemodilution from blood loss have cumulative impacts in decreasing cholesterol; therefore, degree of hypocholesterolemia often reflects severity of illness. The direct correlation between cholesterol and several plasma proteins is mediated by the parallel impact of commonly shared determinants. Cholestasis is associated with a moderation of the degree of hypocholesterolemia. In human sepsis, the poor implications of hypocholesterolemia seem to be aggravated by the simultaneous development of hypertriglyceridemia. Cholesterol and triglyceride levels reflect altered lipoprotein patterns, and the issue is too complex and too poorly understood to be reduced to simple concepts; nevertheless, these simple measurements often represent helpful adjunctive clinical tools. After surgery, in sepsis and various critical illnesses, factors such as severity of the acute phase response, liver dysfunction, and hemodilution from blood loss have cumulative impacts in decreasing cholesterol; therefore, degree of hypocholesterolemia often reflects severity of illness. The direct correlation between cholesterol and several plasma proteins is mediated by the parallel impact of commonly shared determinants. Cholestasis is associated with a moderation of the degree of hypocholesterolemia. In human sepsis, the poor implications of hypocholesterolemia seem to be aggravated by the simultaneous development of hypertriglyceridemia. Cholesterol and triglyceride levels reflect altered lipoprotein patterns, and the issue is too complex and too poorly understood to be reduced to simple concepts; nevertheless, these simple measurements often represent helpful adjunctive clinical tools. (en)
Title	Severe hypocholesterolemia in surgical patients, sepsis, and critical illness Severe hypocholesterolemia in surgical patients, sepsis, and critical illness (en)
skos:prefLabel	Severe hypocholesterolemia in surgical patients, sepsis, and critical illness Severe hypocholesterolemia in surgical patients, sepsis, and critical illness (en)
skos:notation	RIV/00179906:_____/10:10082181!RIV11-MZ0-00179906
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Zadák, Zdeněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	287102
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/10:10082181
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mortality; surgery; critical illness; sepsis; hypocholesterolemia; plasma cholesterol (en)
http://linked.open.../riv/klicoveSlovo	mortality sepsis surgery critical illness hypocholesterolemia plasma cholesterol
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[6CD234150686]
http://linked.open...i/riv/nazevZdroje	Journal of Critical Care
http://linked.open...in/vavai/riv/obor	FJ
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	25
http://linked.open...iv/tvurceVysledku	Zadák, Zdeněk Ardito, Francesco Chiarla, Carlo Clemente, Gennaro Giovannini, Ivo Giuliante, Felice Murazio, Mario Nuzzo, Gennaro Vellone, Maria
http://linked.open...ain/vavai/riv/wos	000283718600008
issn	0883-9441
number of pages	6 (xsd:int)

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