About: The effect of chronic iron losses on liver regeneration in male and female rats

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About: The effect of chronic iron losses on liver regeneration in male and female rats Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We studied the effect of iron deficiency on liver regeneration and innate immunity - respiratory burst of PMN. Wistar rats, males (M) and females (F) had sham withdrawals or males (M-w) and females (F-w) had nine blood withdrawals every week. All rats were sacrificed in 10th week after 67% hepatectomy (PH). We determined blood cell count, respiratory burst (RB), serum prohepcidin, estradiol, iron, iron binding capacity (TIBC) and liver iron stores. Both genders with blood withdrawals had early beginning of liver regeneration after PH. The preconditioning (withdrawals) leads to increase in iron turnover and stores following best reactivity of PMN, rapid decrease in serum prohepcidin, and early initiation of liver regeneration, mainly in females. Females have higher iron turnover, liver iron stores more easily mobilized for blood losses, because next gravidity physiologically begin immediately after birth. We studied the effect of iron deficiency on liver regeneration and innate immunity - respiratory burst of PMN. Wistar rats, males (M) and females (F) had sham withdrawals or males (M-w) and females (F-w) had nine blood withdrawals every week. All rats were sacrificed in 10th week after 67% hepatectomy (PH). We determined blood cell count, respiratory burst (RB), serum prohepcidin, estradiol, iron, iron binding capacity (TIBC) and liver iron stores. Both genders with blood withdrawals had early beginning of liver regeneration after PH. The preconditioning (withdrawals) leads to increase in iron turnover and stores following best reactivity of PMN, rapid decrease in serum prohepcidin, and early initiation of liver regeneration, mainly in females. Females have higher iron turnover, liver iron stores more easily mobilized for blood losses, because next gravidity physiologically begin immediately after birth. (en)
Title	The effect of chronic iron losses on liver regeneration in male and female rats The effect of chronic iron losses on liver regeneration in male and female rats (en)
skos:prefLabel	The effect of chronic iron losses on liver regeneration in male and female rats The effect of chronic iron losses on liver regeneration in male and female rats (en)
skos:notation	RIV/00179906:_____/10:10072332!RIV11-MZ0-00179906
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Palička, Vladimír Živný, Pavel Švejkovská, Klára Vokurková, Doris
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	255905
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/10:10072332
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Liver regeneration; Prohepcidin; Respiratory burst; Iron (en)
http://linked.open.../riv/klicoveSlovo	Iron Respiratory burst Prohepcidin Liver regeneration
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[0590FE93247D]
http://linked.open...i/riv/nazevZdroje	Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, CzechoSK
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	154
http://linked.open...iv/tvurceVysledku	Palička, Vladimír Vokurková, Doris Švejkovská, Klára Živná, Helena Živný, Pavel
http://linked.open...n/vavai/riv/zamer	Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	1213-8118
number of pages	6 (xsd:int)

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