About: Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass

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About: Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In %22on-pump%22 patients, we found an increase in the expression of CD95 median intensity fluorescence (MFI) on granulocytes from a baseline level median=56, (Q 1=45.5, Q3=64) to a median=88, (Q1=62, Q 3=109.5; p{0.01) at the 3rd postoperative day and median=74, (Q1=63, Q3=84.5; p{0.01) at the 7th postoperative day. In %22off-pump%22 patients, granulocyte CD95 MFI was median=55, (Q1=51, Q3=84) before surgery. The significant increase was found on the 3rd postoperative day only; median=90, (Q 1=66; Q3=98; p{0.05). A similar pattern in the CD95 expression was also found if percentage changes of granulocyte CD95 MFI were followed. Moreover, the significantly increased Apo/Fas expression expressed as a percentage change of CD95 MFI was found in %22on-pump%22 patients compared to %22off-pump%22 patients, both at the 3rd postoperative day (p{0.05) and at the 7th postoperative day (p{0.01).10.1177/0267659110363318 In %22on-pump%22 patients, we found an increase in the expression of CD95 median intensity fluorescence (MFI) on granulocytes from a baseline level median=56, (Q 1=45.5, Q3=64) to a median=88, (Q1=62, Q 3=109.5; p{0.01) at the 3rd postoperative day and median=74, (Q1=63, Q3=84.5; p{0.01) at the 7th postoperative day. In %22off-pump%22 patients, granulocyte CD95 MFI was median=55, (Q1=51, Q3=84) before surgery. The significant increase was found on the 3rd postoperative day only; median=90, (Q 1=66; Q3=98; p{0.05). A similar pattern in the CD95 expression was also found if percentage changes of granulocyte CD95 MFI were followed. Moreover, the significantly increased Apo/Fas expression expressed as a percentage change of CD95 MFI was found in %22on-pump%22 patients compared to %22off-pump%22 patients, both at the 3rd postoperative day (p{0.05) and at the 7th postoperative day (p{0.01).10.1177/0267659110363318 (en)
Title	Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass (en)
skos:prefLabel	Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass (en)
skos:notation	RIV/00179906:_____/10:10069732!RIV11-MZ0-00179906
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR9090), Z(MSM0021620812)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Krejsek, Jan Manďák, Jiří Harrer, Jan Andrýs, Ctirad Kuneš, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	294493
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/10:10069732
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	apoptosis; Apo/Fas complex; neutrophil; inflammation; cardiac surgery (en)
http://linked.open.../riv/klicoveSlovo	neutrophil inflammation cardiac surgery apoptosis Apo/Fas complex
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[DA17DA3D4023]
http://linked.open...i/riv/nazevZdroje	Perfusion
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	The use of miniinvasive extracorporeal circuit (mini-CPB) in cardiac surgery
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	25
http://linked.open...iv/tvurceVysledku	Andrýs, Ctirad Harrer, Jan Holická, Monika Krejsek, Jan Koláčková, Martina Manďák, Jiří Kuneš, Pavel
http://linked.open...ain/vavai/riv/wos	000275458800008
http://linked.open...n/vavai/riv/zamer	Chronická onemocnění vznikající na podkladě nepřiměřené reaktivity imunitního systému, jejich patogeneze a možnosti včasné diagnostiky a léčby
issn	0267-6591
number of pages	6 (xsd:int)

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