About: Immunologic Changes in TNF-alpha, sE-selectin, sP-selectin, sICAM-1, and IL-8 in Pediatric Patients Treated for Psoriasis with the Goeckerman Regimen

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Immunologic Changes in TNF-alpha, sE-selectin, sP-selectin, sICAM-1, and IL-8 in Pediatric Patients Treated for Psoriasis with the Goeckerman Regimen Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Psoriáza je chronická zánětlivá choroba, která se často manifestuje u dětí. Prezentovaná studie zjišťovala změny sérových hladin prozánětových cytokinů a solubilní formy adhezních molekul u dětí s psoriázou. Naše výsledky potvrdily kompletní roly imunitních parametrů v imunopatogenezy psoriázy u dětí. Sérová hladina IL-8 se zvýšila po Goeckermanově terapii. Tento fakt indikuje, že chemokinové cesty IL-8 aktivity mohou být modulovány touto terapií, zvláště díky polycyklickým aromatickým uhlovodíkům. (cs) Psoriasis is a chronic inflammatory skin disease which is often manifested during childhood.The present study investigated changes in the serum levels of proinflammatory cytokines and soluble forms of adhesion molecules in children with psoriasis. The observed patient group of 26 children was treated with the Goeckerman regimen. Our findings support the complex role of these immune parameters in the immunopathogenesis of psoriasis in children. The serum level of IL-8 increased after the Goeckerman regimen. This fact indicates that the chemokine pathway of IL-8 activity could be modulated by this treatment, most likely by polycyclic aromatic hydrocarbons. Psoriasis is a chronic inflammatory skin disease which is often manifested during childhood.The present study investigated changes in the serum levels of proinflammatory cytokines and soluble forms of adhesion molecules in children with psoriasis. The observed patient group of 26 children was treated with the Goeckerman regimen. Our findings support the complex role of these immune parameters in the immunopathogenesis of psoriasis in children. The serum level of IL-8 increased after the Goeckerman regimen. This fact indicates that the chemokine pathway of IL-8 activity could be modulated by this treatment, most likely by polycyclic aromatic hydrocarbons. (en)
Title	Immunologic Changes in TNF-alpha, sE-selectin, sP-selectin, sICAM-1, and IL-8 in Pediatric Patients Treated for Psoriasis with the Goeckerman Regimen Imunologické změny v TNF - alfa, sE-selektin, sP-selektin, sICAM-1 a IL-8 u dětských pacientů léčených pro psoriázu Goeckermanovou metodou (cs) Immunologic Changes in TNF-alpha, sE-selectin, sP-selectin, sICAM-1, and IL-8 in Pediatric Patients Treated for Psoriasis with the Goeckerman Regimen (en)
skos:prefLabel	Immunologic Changes in TNF-alpha, sE-selectin, sP-selectin, sICAM-1, and IL-8 in Pediatric Patients Treated for Psoriasis with the Goeckerman Regimen Imunologické změny v TNF - alfa, sE-selektin, sP-selektin, sICAM-1 a IL-8 u dětských pacientů léčených pro psoriázu Goeckermanovou metodou (cs) Immunologic Changes in TNF-alpha, sE-selectin, sP-selectin, sICAM-1, and IL-8 in Pediatric Patients Treated for Psoriasis with the Goeckerman Regimen (en)
skos:notation	RIV/00179906:_____/07:00000357!RIV08-MZ0-00179906
http://linked.open.../vavai/riv/strany	607;612
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Krejsek, Jan Vokurková, Doris Andrýs, Ctirad Kremláček, Jan Hamáková, Květoslava
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	425527
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/07:00000357
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	psoriasis; Goeckerman's therapy; polycyclic aromatic hydrocarbons; TNF - alfa; sE-selectin; sP-selectin; sICAM-1; IL-8 (en)
http://linked.open.../riv/klicoveSlovo	Goeckerman's therapy TNF polycyclic aromatic hydrocarbons psoriasis IL-8 sE-selectin sP-selectin sICAM-1
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[A512FAAD8F0A]
http://linked.open...i/riv/nazevZdroje	Pediatric Dermatology
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Andrýs, Ctirad Krejsek, Jan Kremláček, Jan Vokurková, Doris Hamáková, Květoslava
http://linked.open...n/vavai/riv/zamer	Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	0736-8046
number of pages	6 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software