About: Effect of atorvastatin on non-cholesterol sterol in patients with type 2 diabetes mellitus and cardiovascular disease

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About: Effect of atorvastatin on non-cholesterol sterol in patients with type 2 diabetes mellitus and cardiovascular disease Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Poruchy lipidového metabolismu jsou u diabetiků 2. typu spojeny se zvýšeným rizikem kardiovaskulární morbidity a mortality. V současnosti je diskutováno snížení střevní absorpce a zvýšení jaterní....cholesterolu. Diabetici 2. typu se zvýšenou endogenní~tvorbou cholesterolu jsou zvláště vhodnou skupinou pro léčbu statiny.~ (cs) An increased risk of cardiovascular morbidity and mortality in diabetes mellitus type 2 has been associated with disturbance of lipid homeostasis. Recently, decreased intestinal absorption of cholesterol and increased liver cholesterol production have~been reported. We conclude that in spite the total cholesterol level in diabetics type 2 is not increased, its endogenous synthesis is enhanced. Our results show that the diabetics type 2 with increased serum lathosterol and expressed metabolic syndrome~(mild increased of triglycerides) might represent a suitable group for intensive treatment with statins.~ An increased risk of cardiovascular morbidity and mortality in diabetes mellitus type 2 has been associated with disturbance of lipid homeostasis. Recently, decreased intestinal absorption of cholesterol and increased liver cholesterol production have~been reported. We conclude that in spite the total cholesterol level in diabetics type 2 is not increased, its endogenous synthesis is enhanced. Our results show that the diabetics type 2 with increased serum lathosterol and expressed metabolic syndrome~(mild increased of triglycerides) might represent a suitable group for intensive treatment with statins.~ (en)
Title	Effect of atorvastatin on non-cholesterol sterol in patients with type 2 diabetes mellitus and cardiovascular disease Vliv atorvastatinu na necholesterolové steroly u diabetiků 2. typu a u pacientů s kardiovaskulárním onemocněním (cs) Effect of atorvastatin on non-cholesterol sterol in patients with type 2 diabetes mellitus and cardiovascular disease (en)
skos:prefLabel	Effect of atorvastatin on non-cholesterol sterol in patients with type 2 diabetes mellitus and cardiovascular disease Vliv atorvastatinu na necholesterolové steroly u diabetiků 2. typu a u pacientů s kardiovaskulárním onemocněním (cs) Effect of atorvastatin on non-cholesterol sterol in patients with type 2 diabetes mellitus and cardiovascular disease (en)
skos:notation	RIV/00179906:_____/05:00000462!RIV06-MZ0-00179906
http://linked.open.../vavai/riv/strany	31-36
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NB6999)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Šmahelová, Alena Hyšpler, Radomír Tichá, Alena Zadák, Zdeněk Bláha, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	519244
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/05:00000462
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	non-cholesterol sterols; type 2 diabetes mellitus; atorvastatin; metabolic syndrome; cholesterol turnover (en)
http://linked.open.../riv/klicoveSlovo	atorvastatin type 2 diabetes mellitus cholesterol turnover metabolic syndrome non-cholesterol sterols
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[73E79E1E1E6D]
http://linked.open...i/riv/nazevZdroje	Pharmacological Research
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Atherogenic role of disorders of fatty acid and cholesterol metabolism in coronary atherogenesis in diabetes mellitus type II.
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	51
http://linked.open...iv/tvurceVysledku	Hyšpler, Radomír Tichá, Alena Zadák, Zdeněk Šmahelová, Alena Bláha, Vladimír
issn	1043-6618
number of pages	6 (xsd:int)

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