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| Description
| - Two radiochromic gel dosimeters, Fricke-xylenol orange (FXO) gel and Turnbull Blue (TB) gel, were studied in the scope of the iMERA+ project “Increasing cancer treatment efficacy using 3D brachytherapy” for their feasibility for determination of 3D dose distributions in brachytherapy. Initially, the dose, dose-rate and energy dependence of the gels was investigated. Subsequently, the gels were irradiated by point low-dose-rate source IsoSeed I25.S16 (125I) and high-dose-rate source GammaMed+ (192Ir) and scanned using an optical computed tomography. Optical transmission images of irradiated gels were processed to obtain optical density maps inside the gels which are proportional to the absorbed dose. With pixel resolution of 0.25 mm the detailed 3D dose distributions were reconstructed. The radial dose function between 1.5 and 35 mm from the source and anisotropy function at 10 mm radius were determined and compared to Monte Carlo calculations and TG-43 reference data showing a good agreement. Results revealed that the TB gel conserves sharp dose gradients occurring in the close proximity to the source as this gel does not suffer diffusion of dye created upon irradiation. On the other hand, FXO gel underestimates doses closer than 5 mm from the source due to diffusion, but it has a significantly higher sensitivity which enables convenient measurement of relative doses up to 35 mm from the source. Promising results can already be achieved, as demonstrated in this paper, but further development, especially on gel compositions, has to be carried out.
- Two radiochromic gel dosimeters, Fricke-xylenol orange (FXO) gel and Turnbull Blue (TB) gel, were studied in the scope of the iMERA+ project “Increasing cancer treatment efficacy using 3D brachytherapy” for their feasibility for determination of 3D dose distributions in brachytherapy. Initially, the dose, dose-rate and energy dependence of the gels was investigated. Subsequently, the gels were irradiated by point low-dose-rate source IsoSeed I25.S16 (125I) and high-dose-rate source GammaMed+ (192Ir) and scanned using an optical computed tomography. Optical transmission images of irradiated gels were processed to obtain optical density maps inside the gels which are proportional to the absorbed dose. With pixel resolution of 0.25 mm the detailed 3D dose distributions were reconstructed. The radial dose function between 1.5 and 35 mm from the source and anisotropy function at 10 mm radius were determined and compared to Monte Carlo calculations and TG-43 reference data showing a good agreement. Results revealed that the TB gel conserves sharp dose gradients occurring in the close proximity to the source as this gel does not suffer diffusion of dye created upon irradiation. On the other hand, FXO gel underestimates doses closer than 5 mm from the source due to diffusion, but it has a significantly higher sensitivity which enables convenient measurement of relative doses up to 35 mm from the source. Promising results can already be achieved, as demonstrated in this paper, but further development, especially on gel compositions, has to be carried out. (en)
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| Title
| - Feasibility of radiochromic gels for 3D dosimetry of brachytherapy sources
- Feasibility of radiochromic gels for 3D dosimetry of brachytherapy sources (en)
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| skos:prefLabel
| - Feasibility of radiochromic gels for 3D dosimetry of brachytherapy sources
- Feasibility of radiochromic gels for 3D dosimetry of brachytherapy sources (en)
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| skos:notation
| - RIV/00177016:_____/12:#0000572!RIV13-MSM-00177016
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00177016:_____/12:#0000572
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Gel dosimetry; brachytherapy; radiochromic gels; iMERA+ (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Sochor, Vladimír
- Šolc, Jaroslav
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| issn
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| number of pages
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| http://bibframe.org/vocab/doi
| - 10.1088/0026-1394/49/5/S231
|
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