About: Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects

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About: Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Some findings support the role of serum adipocyte fatty acidbinding protein (A-FABP) as a key pro-inflammatory mediator that links obesity with cardiovascular diseases.The aim of the study was to evaluate the association of A-FABP with endothelial/hemostatic markers, plasminogen activator inhibitor-1, tissue-plasminogen activator, soluble intercellular cell adhesion molecule-1 and soluble vascular cell adhesion molecule-1 in asymptomatic dyslipidemic subjects. We examined 105 dyslipidemic patients without clinical manifestation of atherosclerosis and 50 normolipidemic healthy subjects, who served as a control group. Except of endothelial/hemostatic markers, anthropometric and lipid parameters, markers of insulin resistance and inflammation were assessed. Conclusion: Study displayed an independent positive association of A-FABP with vWF in clinically asymptomatic dyslipidemic subjects. Contribution of A-FABP in the process of endothelial dysfunction could help to explain the role of abesity in cardiovascular damage. Some findings support the role of serum adipocyte fatty acidbinding protein (A-FABP) as a key pro-inflammatory mediator that links obesity with cardiovascular diseases.The aim of the study was to evaluate the association of A-FABP with endothelial/hemostatic markers, plasminogen activator inhibitor-1, tissue-plasminogen activator, soluble intercellular cell adhesion molecule-1 and soluble vascular cell adhesion molecule-1 in asymptomatic dyslipidemic subjects. We examined 105 dyslipidemic patients without clinical manifestation of atherosclerosis and 50 normolipidemic healthy subjects, who served as a control group. Except of endothelial/hemostatic markers, anthropometric and lipid parameters, markers of insulin resistance and inflammation were assessed. Conclusion: Study displayed an independent positive association of A-FABP with vWF in clinically asymptomatic dyslipidemic subjects. Contribution of A-FABP in the process of endothelial dysfunction could help to explain the role of abesity in cardiovascular damage. (en)
Title	Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects (en)
skos:prefLabel	Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects (en)
skos:notation	RIV/00098892:_____/12:#0000343!RIV13-MZ0-00098892
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(NS10284), S
http://linked.open...iv/cisloPeriodika	Suppl. 2
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Novotný, Dalibor
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Olomouc
http://linked.open...dnocenehoVysledku	164839
http://linked.open...ai/riv/idVysledku	RIV/00098892:_____/12:#0000343
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adipocyte fatty acid-binding protein, von Willebrand factor, tissue-plasminogen activator, adhesion molecules, dyslipidemia (en)
http://linked.open.../riv/klicoveSlovo	adipocyte fatty acid-binding protein adhesion molecules dyslipidemia tissue-plasminogen activator von Willebrand factor
http://linked.open...odStatuVydavatele	SE - Švédské království
http://linked.open...ontrolniKodProRIV	[C39887CFC862]
http://linked.open...i/riv/nazevZdroje	Neuroendocrinology Letters
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Dyslipidemia and prehypertension - association of dyslipidemic phenotypes with prevalence of prehypertension. Association of prehypertension with markers of insulin resistance, inflammation, endothelial dysfunction and subclinical atherosclerosis.
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	33
http://linked.open...iv/tvurceVysledku	Karásek, David Novotný, Dalibor
issn	0172-780X
number of pages	6 (xsd:int)

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