About: Pemphigus vulgaris treated with adalimumab: case study

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The study describes the case of a patient with a clinical and histopathological diagnosis of pemphigus vulgaris accompanied by severe side-effects of combined immunosuppressive therapy, who achieved a remission of the disease with adalimumab. Pemphigus vulgaris is a chronic blistering disease of the skin and mucous membranes. Before corticosteroids were introduced, mortality was high. Corticosteroids are currently used as first-line therapy. To reduce the dose of corticosteroids, therapeutic combinations with corticosteroid-sparing immunosuppressive agents are used. The therapy brings a number of complications due to its side effects. To achieve a remission of the disease by treating our patient with combined immunosuppressives, we administered adalimumab and achieved a very good clinical response. The study describes the case of a patient with a clinical and histopathological diagnosis of pemphigus vulgaris accompanied by severe side-effects of combined immunosuppressive therapy, who achieved a remission of the disease with adalimumab. Pemphigus vulgaris is a chronic blistering disease of the skin and mucous membranes. Before corticosteroids were introduced, mortality was high. Corticosteroids are currently used as first-line therapy. To reduce the dose of corticosteroids, therapeutic combinations with corticosteroid-sparing immunosuppressive agents are used. The therapy brings a number of complications due to its side effects. To achieve a remission of the disease by treating our patient with combined immunosuppressives, we administered adalimumab and achieved a very good clinical response. (en)
Title	Pemphigus vulgaris treated with adalimumab: case study Pemphigus vulgaris treated with adalimumab: case study (en)
skos:prefLabel	Pemphigus vulgaris treated with adalimumab: case study Pemphigus vulgaris treated with adalimumab: case study (en)
skos:notation	RIV/00064211:_____/12:#0000211!RIV14-MZ0-00064211
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Vojáčková, Naděžda Hercogová, Jana Fialová, Jorga Vaňousová, Daniela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Nemocnice Na Bulovce
http://linked.open...dnocenehoVysledku	158102
http://linked.open...ai/riv/idVysledku	RIV/00064211:_____/12:#0000211
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adalimumab; biological therapy; corticosteroids; pemphigus vulgaris; infliximab (en)
http://linked.open.../riv/klicoveSlovo	adalimumab pemphigus vulgaris biological therapy infliximab corticosteroids
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[D9307DD7D8D1]
http://linked.open...i/riv/nazevZdroje	Dermatologic Therapy
http://linked.open...in/vavai/riv/obor	FO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	25
http://linked.open...iv/tvurceVysledku	Vojáčková, Naděžda Fialová, Jorga Vaňousová, Daniela Hecogová, Jana
http://linked.open...ain/vavai/riv/wos	000304088300011
issn	1396-0296
number of pages	3 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/j.1529-8019.2012.01433.x

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