About: An imported case of bloody diarrhea in the Czech Republic caused by a hybrid enteroaggregative hemorrhhagic Escherichia coli (EAHEC) O104:H4 strain associated with the large outbreak in Germany

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About: An imported case of bloody diarrhea in the Czech Republic caused by a hybrid enteroaggregative hemorrhhagic Escherichia coli (EAHEC) O104:H4 strain associated with the large outbreak in Germany Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A large outbreak caused by a rare Shiga toxinproducing Escherichia coli serotype O104:H4 occurred in Germany in May to July 2011. The National Reference Laboratory for E. coli and Shigella investigated the stool sample from an American tourist with bloody diarrhea who arrived in the Czech Republic from Germany where she consumed salads with raw vegetable a week ago. Using culture of the enriched stool on extended-spectrum β- lactamase agar, we isolated E. coli strain which belonged to serotype O104:H4 as determined by conventional and molecular serotyping. The strain contained the major virulence characteristics of enterohemorrhagic E. coli (stx2 encoding Shiga toxin 2) and enteroaggregative E. coli (aggA encoding aggregative adherence fimbriae I). This unique combination of virulence traits demonstrated that this strain belongs to the hybrid enteroaggregative hemorrhagic E. coli clone which caused the German outbreak. Using advanced culture and molecular biological approaches is the prerequisite for identification of new, unusual pathogens. A large outbreak caused by a rare Shiga toxinproducing Escherichia coli serotype O104:H4 occurred in Germany in May to July 2011. The National Reference Laboratory for E. coli and Shigella investigated the stool sample from an American tourist with bloody diarrhea who arrived in the Czech Republic from Germany where she consumed salads with raw vegetable a week ago. Using culture of the enriched stool on extended-spectrum β- lactamase agar, we isolated E. coli strain which belonged to serotype O104:H4 as determined by conventional and molecular serotyping. The strain contained the major virulence characteristics of enterohemorrhagic E. coli (stx2 encoding Shiga toxin 2) and enteroaggregative E. coli (aggA encoding aggregative adherence fimbriae I). This unique combination of virulence traits demonstrated that this strain belongs to the hybrid enteroaggregative hemorrhagic E. coli clone which caused the German outbreak. Using advanced culture and molecular biological approaches is the prerequisite for identification of new, unusual pathogens. (en)
Title	An imported case of bloody diarrhea in the Czech Republic caused by a hybrid enteroaggregative hemorrhhagic Escherichia coli (EAHEC) O104:H4 strain associated with the large outbreak in Germany An imported case of bloody diarrhea in the Czech Republic caused by a hybrid enteroaggregative hemorrhhagic Escherichia coli (EAHEC) O104:H4 strain associated with the large outbreak in Germany (en)
skos:prefLabel	An imported case of bloody diarrhea in the Czech Republic caused by a hybrid enteroaggregative hemorrhhagic Escherichia coli (EAHEC) O104:H4 strain associated with the large outbreak in Germany An imported case of bloody diarrhea in the Czech Republic caused by a hybrid enteroaggregative hemorrhhagic Escherichia coli (EAHEC) O104:H4 strain associated with the large outbreak in Germany (en)
skos:notation	RIV/00064211:_____/12:#0000209!RIV14-MZ0-00064211
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Roháčová, Hana Reisingerová, Marie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Nemocnice Na Bulovce
http://linked.open...dnocenehoVysledku	121974
http://linked.open...ai/riv/idVysledku	RIV/00064211:_____/12:#0000209
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	emorrhagic Eschericha coli; hemorrhagic diarrhea; hemolytic-uremic syndrom; shiga toxin (en)
http://linked.open.../riv/klicoveSlovo	emorrhagic Eschericha coli hemolytic-uremic syndrom hemorrhagic diarrhea shiga toxin
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[B503EA6D582D]
http://linked.open...i/riv/nazevZdroje	Folia microbiologica
http://linked.open...in/vavai/riv/obor	FN
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	57
http://linked.open...iv/tvurceVysledku	Roháčová, Hana Petráš, Petr Marejková, Monika Reisingerová, Marie
http://linked.open...ain/vavai/riv/wos	000303679900001
issn	0015-5632
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s12223-011-0095-0

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