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Description
| - Stanovení prevalence GBV-c/HGV infekce u HIV pozitivních pacientů a zjišťování možného vlivu GBV-c/HGV na průběh infekce HIV stanovením imulogických a virologických markerů progrese HIV infekce. METODIKA: V roce 2002 a 2003 jsme vyšetřili séra u 273 HIV pozitivních pacientů z AIDS-centra FN Bulovka Praha na přítomnost markerů GBV-c/HGV infekce semikvantitativním stanovením HGV PCR a anti-E2 protilátek metodou ELISA. 271 sérových vzorků bylo vyšetřeno na HGV PCR a 269 vzorků na antiE2.V den odběru byla zjišťována HIV virémie a počet CD4 lymfocytů. Závislost počtu CD4 lymfocytů a virové nálože HIV na infekci virem HGV jsme zjišťovali Spearmanovým testem. VÝSLEDKY: 89 (33,3%) pacientů mělo pozitivní PCR HGV a 101 (38,5%) pacientů mělo pozitivní test anti-E2 metodou ELISA. Statisticky významný vliv GBV-c/HGV infekce u HIV infikovaných na počet CD4 lymfocytů a na virovou nálož HIV nebyl v našem souboru prokázán. ZÁVĚR: Naše sledování nepotvrzuje vliv GBV-c/HGV infekce na základni prediktivní laboratorní (cs)
- Objectives: Assessment of prevalence of GBV-c/HGV infection in HIV-infected patients and evaluating of a possible influence of GBV-c/HGV on the course of HIV infection by assessment of immunological and virological markers of progression of HIV infection. Methods: We have investigated seras of 273 HIV-infected patients from AIDS Center of the University Hospital Na Bulovce Prague during 2002-2003. Our target was to assess the presence of markers of GBV-c/HGV infection by semiquantitative HGV PCR evaluation and anti-E2 antibodies by ELISA testing. 271 of serum samples were tested for HGV PCR and 269 samples were tested for anti-E2 antibodies. HIV viral load and CD4 count were tested concurrently. We used Spearman´s test to rule out the dependency of CD4 count and HIV viral load on HGV infection. Results: 89 (33,3%) of patients were positive in PCR HGV test and 101 (38,5%) of patients were positive in anti E2-ELISA. No statistically significant efect of GBV-c/HGV infection was observed on CD4 count an
- Objectives: Assessment of prevalence of GBV-c/HGV infection in HIV-infected patients and evaluating of a possible influence of GBV-c/HGV on the course of HIV infection by assessment of immunological and virological markers of progression of HIV infection. Methods: We have investigated seras of 273 HIV-infected patients from AIDS Center of the University Hospital Na Bulovce Prague during 2002-2003. Our target was to assess the presence of markers of GBV-c/HGV infection by semiquantitative HGV PCR evaluation and anti-E2 antibodies by ELISA testing. 271 of serum samples were tested for HGV PCR and 269 samples were tested for anti-E2 antibodies. HIV viral load and CD4 count were tested concurrently. We used Spearman´s test to rule out the dependency of CD4 count and HIV viral load on HGV infection. Results: 89 (33,3%) of patients were positive in PCR HGV test and 101 (38,5%) of patients were positive in anti E2-ELISA. No statistically significant efect of GBV-c/HGV infection was observed on CD4 count an (en)
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Title
| - Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease.
- Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease. (en)
- Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease./Prevalence GBV-c/HGV u HIV infikovaných pacientů a možný význam koinfekce pro vývoj nemoci (cs)
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skos:prefLabel
| - Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease.
- Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease. (en)
- Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease./Prevalence GBV-c/HGV u HIV infikovaných pacientů a možný význam koinfekce pro vývoj nemoci (cs)
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skos:notation
| - RIV/00064211:_____/04:00011348!RIV/2005/MZ0/L10005/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00064211:_____/04:00011348
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - prevalence;GBV/c/HGV;HIV;infected;patients;influence;coinfection;course;disease;immunological;virological;markers;progression;infection;273;infected;patients;AIDS;Center;Prague;viral;load;CD4;dependency;HGV PCR;33%;positive;anti-E2;38,5%;effect;predictiv (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Clinical Microbiology and Infection
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Rozsypal, Hanuš
- Staňková, Marie
- Aster, Viktor
- König, Jaroslav
- Procházka, Bohumil
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issn
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number of pages
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