About: Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome

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About: Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1002/mus.23657
Description	Introduction: Myasthenia gravis is an autoimmune disease marked by neuromuscular transmission failure at the neuromuscular junction. Castleman disease is a rare lymphoproliferative disease characterized by non-cancerous angiofolicular hyperplasia of lymphatic tissue. Methods and results: We describe a young man with rapid, successive manifestations of myasthenia gravis, a solitary form of Castleman disease, pemphigus vulgaris, and anti-phospholipid syndrome, which resulted in 2 ischemic cerebrovascular events that caused a severe central neurological deficit. Discussion: We were unable to find a similar case in the literature, but we hypothesize that the temporal concidence of these clinical entities may be related to a common immunological pathway, such as B-cell activation. Therefore, we treated the patient with an immunosuppressant and anticoagulant treatment, as well as rituximab, a monoclonal antibody therapy against CD20+. Muscle Nerve 47:447-451, 2013 Introduction: Myasthenia gravis is an autoimmune disease marked by neuromuscular transmission failure at the neuromuscular junction. Castleman disease is a rare lymphoproliferative disease characterized by non-cancerous angiofolicular hyperplasia of lymphatic tissue. Methods and results: We describe a young man with rapid, successive manifestations of myasthenia gravis, a solitary form of Castleman disease, pemphigus vulgaris, and anti-phospholipid syndrome, which resulted in 2 ischemic cerebrovascular events that caused a severe central neurological deficit. Discussion: We were unable to find a similar case in the literature, but we hypothesize that the temporal concidence of these clinical entities may be related to a common immunological pathway, such as B-cell activation. Therefore, we treated the patient with an immunosuppressant and anticoagulant treatment, as well as rituximab, a monoclonal antibody therapy against CD20+. Muscle Nerve 47:447-451, 2013 (en)
Title	Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome (en)
skos:prefLabel	Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome (en)
skos:notation	RIV/00064203:_____/13:10188935!RIV14-MZ0-00064203
http://linked.open...avai/riv/aktivita	I S Z
http://linked.open...avai/riv/aktivity	I, S, Z(MSM0021620849)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Schützner, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	90287
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/13:10188935
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pemphigus vulgaris; myasthenia gravis; interleukin-6; Castleman disease; anti-phospholipid syndrome (en)
http://linked.open.../riv/klicoveSlovo	anti-phospholipid syndrome interleukin-6 pemphigus vulgaris Castleman disease myasthenia gravis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[193D1DE05E04]
http://linked.open...i/riv/nazevZdroje	Muscle and Nerve
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	47
http://linked.open...iv/tvurceVysledku	Ehler, Edvard Schützner, Jan Piťha, Jiří Jakubíková, Michala Latta, Jan
http://linked.open...ain/vavai/riv/wos	000315401500021
http://linked.open...n/vavai/riv/zamer	Neuropsychiatrické aspekty neurodegenerativních onemocnění
issn	0148-639X
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/mus.23657

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