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  • Objective: In 2005, the Inflammatory Bowel Disease (IBD) Working Group of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition published consensus guidelines on the diagnostic workup of paediatric IBD, the Porto criteria. According to these guidelines, children suspected of having IBD should undergo an oesophagogastroduodenoscopy (OGD), ileocolonoscopy, and (except in cases of definitive ulcerative colitis) adequate imaging of the small bowel. To audit and evaluate the diagnostic workup of paediatric patients with IBD in Europe, the Working Group created EUROKIDS, a prospective, Web-based registry of newly diagnosed paediatric patients with IBD. Methods: Patients with IBD (ages 0-18 years) were registered in 44 centres in 18 countries. Data on diagnostic workup were analysed according to the year of diagnosis, type of IBD, and centre size. Diagnostic yield of OGD and ileal intubation were evaluated. Results: Between 2004 and 2009, 2087 newly diagnosed patients were correctly registered. Both OGD and ileocolonoscopy had been performed in 64% of all of the patients and increased significantly from year 1 (52 %) to 5 (71%, P<0.001). Small-bowel follow-through use decreased during the years (year 1 n = 213, year 5 n=108; P<0.001), whereas magnetic resonance imaging use increased (year 1 n = 25, year 5 n = 171; P<0.001). Patients diagnosed as having Crohn disease (CD, 59%) and ulcerative colitis (58%) were more likely to have had a complete diagnostic workup than patients diagnosed as having IBD unclassified (45%). In CD, the diagnostic yield of OGD was 7.5% and the yield of ileal intubation was 13%. Conclusions: The quality of diagnostic workup in paediatric patients with IBD increased steadily between 2004 and 2009. Small-bowel imaging by magnetic resonance imaging superseded the use of small-bowel follow-through. OGD and ileal intubation contributed to a definitive diagnosis of CD.
  • Objective: In 2005, the Inflammatory Bowel Disease (IBD) Working Group of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition published consensus guidelines on the diagnostic workup of paediatric IBD, the Porto criteria. According to these guidelines, children suspected of having IBD should undergo an oesophagogastroduodenoscopy (OGD), ileocolonoscopy, and (except in cases of definitive ulcerative colitis) adequate imaging of the small bowel. To audit and evaluate the diagnostic workup of paediatric patients with IBD in Europe, the Working Group created EUROKIDS, a prospective, Web-based registry of newly diagnosed paediatric patients with IBD. Methods: Patients with IBD (ages 0-18 years) were registered in 44 centres in 18 countries. Data on diagnostic workup were analysed according to the year of diagnosis, type of IBD, and centre size. Diagnostic yield of OGD and ileal intubation were evaluated. Results: Between 2004 and 2009, 2087 newly diagnosed patients were correctly registered. Both OGD and ileocolonoscopy had been performed in 64% of all of the patients and increased significantly from year 1 (52 %) to 5 (71%, P<0.001). Small-bowel follow-through use decreased during the years (year 1 n = 213, year 5 n=108; P<0.001), whereas magnetic resonance imaging use increased (year 1 n = 25, year 5 n = 171; P<0.001). Patients diagnosed as having Crohn disease (CD, 59%) and ulcerative colitis (58%) were more likely to have had a complete diagnostic workup than patients diagnosed as having IBD unclassified (45%). In CD, the diagnostic yield of OGD was 7.5% and the yield of ileal intubation was 13%. Conclusions: The quality of diagnostic workup in paediatric patients with IBD increased steadily between 2004 and 2009. Small-bowel imaging by magnetic resonance imaging superseded the use of small-bowel follow-through. OGD and ileal intubation contributed to a definitive diagnosis of CD. (en)
Title
  • Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry
  • Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry (en)
skos:prefLabel
  • Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry
  • Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry (en)
skos:notation
  • RIV/00064203:_____/12:8590!RIV13-MZ0-00064203
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 130943
http://linked.open...ai/riv/idVysledku
  • RIV/00064203:_____/12:8590
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • diagnostic workup; diagnostic yield; inflammatory bowel disease; OGD; paediatrics (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [B3F55723A7AF]
http://linked.open...i/riv/nazevZdroje
  • Journal of Pediatric Gastroenterology and Nutrition
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 54
http://linked.open...iv/tvurceVysledku
  • Bronský, Jiří
  • Nevoral, Jiří
  • Veres, G.
  • Hradský, Ondřej
  • Ravelli, A.
  • Amil, Dias, J
  • Bie, CI
  • Biervliet, S.
  • Bochenek, K.
  • Buderus, S.
  • Bujanover, Y.
  • Chong, SK
  • Cucchiara, S.
  • Dias, J. A.
  • Eglite, L.
  • Escher, JC
  • Fell, JM
  • Finkel, Y.
  • Henker, J.
  • Hildebrand, H.
  • Holmquist, L.
  • Hugot, J. P.
  • Keller, K.
  • Koletzko, S.
  • Koláček, S.
  • Lazowska, I.
  • Levine, A.
  • Lionetti, P.
  • Malmborg, P.
  • Maly, J.
  • Murphy, MS
  • Orel, R.
  • Paerregaard, A.
  • Perminow, G.
  • Ridder, L.
  • Roma, E.
  • Ruemmele, F.
  • Sandhu, BK
  • Sladek, M.
  • Socha, P.
  • Spray, C.
  • Staiano, A.
  • Stordal, K.
  • Trindade, E.
  • Veereman, G.
http://linked.open...ain/vavai/riv/wos
  • 000300760200013
issn
  • 0277-2116
number of pages
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