About: Design, history and results of the Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) randomised controlled trial     Goto   Sponge   NotDistinct   Permalink

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Description
  • From the study design, 16,000 people were to be followed for approximately 5.5 years. However, the trial was stopped prematurely because of regulatory concerns after a mean of 162 days without consideration of the accrued data. In the TZD arm, the cardiovascular outcome occurred in five participants (0.9%) in the placebo groups and three participants (0.4%) in the TZD groups (two allocated to pioglitazone, one to rosiglitazone). In the vitamin D arm, the primary outcome occurred in three participants (0.5%) in the placebo group and in two participants (0.3%) receiving vitamin D. Adverse events were comparable in all groups.
  • From the study design, 16,000 people were to be followed for approximately 5.5 years. However, the trial was stopped prematurely because of regulatory concerns after a mean of 162 days without consideration of the accrued data. In the TZD arm, the cardiovascular outcome occurred in five participants (0.9%) in the placebo groups and three participants (0.4%) in the TZD groups (two allocated to pioglitazone, one to rosiglitazone). In the vitamin D arm, the primary outcome occurred in three participants (0.5%) in the placebo group and in two participants (0.3%) receiving vitamin D. Adverse events were comparable in all groups. (en)
Title
  • Design, history and results of the Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) randomised controlled trial
  • Design, history and results of the Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) randomised controlled trial (en)
skos:prefLabel
  • Design, history and results of the Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) randomised controlled trial
  • Design, history and results of the Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) randomised controlled trial (en)
skos:notation
  • RIV/00064203:_____/12:8584!RIV13-MZ0-00064203
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 130293
http://linked.open...ai/riv/idVysledku
  • RIV/00064203:_____/12:8584
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Cardiovascular disease; Pioglitazone; Placebo-controlled randomised trial; Rosiglitazone; Type 2 diabetes; Vitamin D (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [9A12555E46FA]
http://linked.open...i/riv/nazevZdroje
  • Diabetologia
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 55
http://linked.open...iv/tvurceVysledku
  • Diaz, R.
  • Kvapil, Milan
  • Yusuf, S.
  • Pogue, J.
  • Afzal, R.
  • Ariani, M.
  • Arsenault, J.
  • Barzilay, J.
  • Bilazarian, S.
  • Bommer, W.
  • Bosch, J.
  • Brautigam, D.
  • Burke, M.
  • Castelli, J.
  • Cushman, W.
  • Dagenais, G.
  • Feinglos, M.
  • Forbes, B.
  • Force, R.
  • Gerstein, H.
  • Giddings, S.
  • Gillespie, E.
  • Hamaty, M.
  • Hardman, C.
  • Haywood, L.
  • Ho, L.
  • Hollander, P.
  • Holman, R.
  • Joldersma, L.
  • Karl, D.
  • Kashyap, M.
  • Linz, P.
  • Lui, S.
  • MacRae, L.
  • Marshall, T.
  • Ng, J.
  • Nicol, P.
  • Nyenwe, E.
  • Probstfield, J.
  • Punthakee, Z.
  • Raghavan, V.
  • Ramachandran, A.
  • Reznick, DeMarco, Y
  • Richardson, L.
  • Riddle, M.
  • Roberts, S.
  • Ryden, L.
  • Solbrig, R.
  • Sperl, J.
  • Stevens, C.
  • Sweeney, M.
  • Tosta, F.
  • Wasala, L.
  • Webster, J.
  • Whate, A.
  • White, J.
  • Wu, P.
  • Wyne, K.
  • Yuan, F.
  • Zinman, B.
  • Zotova, E.
http://linked.open...ain/vavai/riv/wos
  • 000297739000009
issn
  • 0012-186X
number of pages
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