About: Microalbuminuria in children with primary and white-coat hypertension     Goto   Sponge   NotDistinct   Permalink

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  • Microalbuminuria serves as an early marker of hypertension-related renal damage in adults. However, data on the prevalence of microalbuminuria in paediatric hypertensive patients in general and in children with white-coat hypertension (WCH) specifically are lacking. The aim of our study was to investigate the prevalence of microalbuminuria in children with primary hypertension (PH) and WCH, respectively. This was a retrospective case review of children with PH and WCH treated at three paediatric nephrology centres. Untreated children with either form of hypertension for whom measurements of urinary albumin excretion (UAE) had been performed were enrolled in the study. The study cohort comprised 52 children (39 boys) with hypertension (26 children with PH, 26 with WCH). Microalbuminuria (> 3.2 mg/mmol creatinine) was present in 20% of children with PH and none of the children with WCH (p < 0.01). Children with PH had a higher median UAE than those with WCH (1.27 +/- 1.92 vs. 0.66 +/- 0.46 mg/mmol creatinine, p < 0.05). Based on these results, we suggest that children with PH have an increased prevalence of microalbuminuria, while children with WCH show no signs of hypertension-related renal damage.
  • Microalbuminuria serves as an early marker of hypertension-related renal damage in adults. However, data on the prevalence of microalbuminuria in paediatric hypertensive patients in general and in children with white-coat hypertension (WCH) specifically are lacking. The aim of our study was to investigate the prevalence of microalbuminuria in children with primary hypertension (PH) and WCH, respectively. This was a retrospective case review of children with PH and WCH treated at three paediatric nephrology centres. Untreated children with either form of hypertension for whom measurements of urinary albumin excretion (UAE) had been performed were enrolled in the study. The study cohort comprised 52 children (39 boys) with hypertension (26 children with PH, 26 with WCH). Microalbuminuria (> 3.2 mg/mmol creatinine) was present in 20% of children with PH and none of the children with WCH (p < 0.01). Children with PH had a higher median UAE than those with WCH (1.27 +/- 1.92 vs. 0.66 +/- 0.46 mg/mmol creatinine, p < 0.05). Based on these results, we suggest that children with PH have an increased prevalence of microalbuminuria, while children with WCH show no signs of hypertension-related renal damage. (en)
Title
  • Microalbuminuria in children with primary and white-coat hypertension
  • Microalbuminuria in children with primary and white-coat hypertension (en)
skos:prefLabel
  • Microalbuminuria in children with primary and white-coat hypertension
  • Microalbuminuria in children with primary and white-coat hypertension (en)
skos:notation
  • RIV/00064203:_____/12:8053!RIV13-MZ0-00064203
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, Z(MZ0FNM2005)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 150302
http://linked.open...ai/riv/idVysledku
  • RIV/00064203:_____/12:8053
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Microalbuminuria; Blood pressure; Ambulatory blood pressure monitoring; Primary hypertension; White-coat hypertension; Children; left-ventricular hypertrophy; ambulatory blood-pressure; target-organ damage; masked hypertension; adolescents; determinants; prevalence; frequency; disease; harvest (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [C9168EAFF22E]
http://linked.open...i/riv/nazevZdroje
  • Pediatric Nephrology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 27
http://linked.open...iv/tvurceVysledku
  • Seeman, Tomáš
  • John, U.
  • Palyzova, D.
  • Pohl, M.
http://linked.open...ain/vavai/riv/wos
  • 000299506100017
http://linked.open...n/vavai/riv/zamer
issn
  • 0931-041X
number of pages
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