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Description
| - Introduction: Little is known about the prognosis of moderate versus critical carotid stenosis treated by carotid artery stenting (CAS). Material and methods: This was a retrospective analysis of a single-centre registry including 271 consecutive patients (69 +/- 9 years, 87% at high risk for surgery), in whom 308 procedures were performed. The study included both symptomatic (>= 50% carotid artery stenosis) and asymptomatic (>= 70% carotid artery stenosis) patients. The primary endpoint was the rate of adverse events during follow-up (range 1-48 months), defined as all-cause death or stroke. Results: We treated 115 critical and 193 moderate stenoses and implanted 318 stents (56% with closed cell design). Embolic protection systems were used in 296 cases (96%). The technical success rate was 98.2% in the critical stenoses group and 99% in the moderate group (NS). During follow-up, the incidence of the primary endpoint was 12.9% (13 pts) in the critical stenoses group and 14.7% (25 pts) in the moderate stenoses group (estimated 3-year freedom from death/stroke was 0.844 vs. 0.812; log-rank test p = 0.983). Left ventricular ejection fraction < 40%, significant contralateral carotid artery occlusion or stenosis and renal insufficiency were identified as significant predictors of the primary endpoint (p < 0.03). Conclusions: Carotid artery stenting with embolic protection systems in patients at high risk for carotid endarterectomy is safe. Patients with initially moderate and critical stenoses have an identical mid-term prognosis with regard to death and stroke.
- Introduction: Little is known about the prognosis of moderate versus critical carotid stenosis treated by carotid artery stenting (CAS). Material and methods: This was a retrospective analysis of a single-centre registry including 271 consecutive patients (69 +/- 9 years, 87% at high risk for surgery), in whom 308 procedures were performed. The study included both symptomatic (>= 50% carotid artery stenosis) and asymptomatic (>= 70% carotid artery stenosis) patients. The primary endpoint was the rate of adverse events during follow-up (range 1-48 months), defined as all-cause death or stroke. Results: We treated 115 critical and 193 moderate stenoses and implanted 318 stents (56% with closed cell design). Embolic protection systems were used in 296 cases (96%). The technical success rate was 98.2% in the critical stenoses group and 99% in the moderate group (NS). During follow-up, the incidence of the primary endpoint was 12.9% (13 pts) in the critical stenoses group and 14.7% (25 pts) in the moderate stenoses group (estimated 3-year freedom from death/stroke was 0.844 vs. 0.812; log-rank test p = 0.983). Left ventricular ejection fraction < 40%, significant contralateral carotid artery occlusion or stenosis and renal insufficiency were identified as significant predictors of the primary endpoint (p < 0.03). Conclusions: Carotid artery stenting with embolic protection systems in patients at high risk for carotid endarterectomy is safe. Patients with initially moderate and critical stenoses have an identical mid-term prognosis with regard to death and stroke. (en)
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Title
| - Comparison of mid-term outcomes of carotid artery stenting for moderate versus critical stenosis
- Comparison of mid-term outcomes of carotid artery stenting for moderate versus critical stenosis (en)
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skos:prefLabel
| - Comparison of mid-term outcomes of carotid artery stenting for moderate versus critical stenosis
- Comparison of mid-term outcomes of carotid artery stenting for moderate versus critical stenosis (en)
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skos:notation
| - RIV/00064203:_____/12:7984!RIV13-MZ0-00064203
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00064203:_____/12:7984
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - carotid stenosis; stenting; follow-up; endarterectomy; protection; safety; trial (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Archives of Medical Science
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hájek, Petr
- Malý, Martin
- Martinkovičová, Lucia
- Tomašov, Pavol
- Veselka, Josef
- Zemánek, David
- Zimolová, Petra
- Špaček, Miloslav
- Tesař, David
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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