About: Control of Hypertension in Treated Children and Its Association With Target Organ Damage

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.ncbi.nlm.nih.gov/pubmed/22089110
Description	BACKGROUND The aim of our study was to investigate the control of hypertension (HT) in treated children using ambulatory blood pressure (BP) monitoring (ABPM), METHODS We retrospectively reviewed all ABPM studies in our center, Controlled HT was defined as systolic and diastolic BP index (patients' BP divided by the 95th percentile) at daytime and nighttime <1,0 or alternatively as BP load (percentage of BP readings above the 95th percentile) <25% in children on antihypertensive therapy, RESULTS A total of 195 ABPM studies were included, The mean age was 13,6 +/- 4,0 years, One hundred and thirty two children had renoparenchymal HT, 10 renovascular (RVH), 10 endocrine, 4 cardiovascular, 29 primary (PH) and 5 children other forms of HT, 53% of all children had controlled HT, There was no difference in the prevalence of controlled HT between primary and secondary HI (52% and 53%) using the BP index criterion, Children with renoparenchymal HT had significantly better control of HT than children with RVH (58% vs, 20% P = 0,02), The use of angiotensin-converting enzyme inhibitors (ACEI) monotherapy was significantly more effective in controlling HT than the use of calcium-channel blockers (CCB, P = 0,02),The prevalence of left ventricular hypertrophy in children with uncontrolled HT (assessed in 58 patients) was significantly higher than in children with controlled HT (46% vs, 13%, P < 0,01), CONCLUSIONS This is the first pediatric study, to our knowledge, on BP control in hypertensive children using ABPM, It indicates that control of HT is inadequate in similar to 50% of treated children, Inadequate control of HT is associated with target organ damage in this population, BACKGROUND The aim of our study was to investigate the control of hypertension (HT) in treated children using ambulatory blood pressure (BP) monitoring (ABPM), METHODS We retrospectively reviewed all ABPM studies in our center, Controlled HT was defined as systolic and diastolic BP index (patients' BP divided by the 95th percentile) at daytime and nighttime <1,0 or alternatively as BP load (percentage of BP readings above the 95th percentile) <25% in children on antihypertensive therapy, RESULTS A total of 195 ABPM studies were included, The mean age was 13,6 +/- 4,0 years, One hundred and thirty two children had renoparenchymal HT, 10 renovascular (RVH), 10 endocrine, 4 cardiovascular, 29 primary (PH) and 5 children other forms of HT, 53% of all children had controlled HT, There was no difference in the prevalence of controlled HT between primary and secondary HI (52% and 53%) using the BP index criterion, Children with renoparenchymal HT had significantly better control of HT than children with RVH (58% vs, 20% P = 0,02), The use of angiotensin-converting enzyme inhibitors (ACEI) monotherapy was significantly more effective in controlling HT than the use of calcium-channel blockers (CCB, P = 0,02),The prevalence of left ventricular hypertrophy in children with uncontrolled HT (assessed in 58 patients) was significantly higher than in children with controlled HT (46% vs, 13%, P < 0,01), CONCLUSIONS This is the first pediatric study, to our knowledge, on BP control in hypertensive children using ABPM, It indicates that control of HT is inadequate in similar to 50% of treated children, Inadequate control of HT is associated with target organ damage in this population, (en)
Title	Control of Hypertension in Treated Children and Its Association With Target Organ Damage Control of Hypertension in Treated Children and Its Association With Target Organ Damage (en)
skos:prefLabel	Control of Hypertension in Treated Children and Its Association With Target Organ Damage Control of Hypertension in Treated Children and Its Association With Target Organ Damage (en)
skos:notation	RIV/00064203:_____/12:7980!RIV13-MZ0-00064203
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MZ0FNM2005)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Gilík, Jiří Seeman, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	128690
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/12:7980
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	antihypertensive therapy; blood pressure; children; control; hypertension; left ventricular hypertrophy; left-ventricular hypertrophy; blood-pressure control; chronic kidney-disease; antihypertensive therapy; cardiovascular-disease; practice guidelines; renal-failure; task-force; adolescents; management (en)
http://linked.open.../riv/klicoveSlovo	children chronic kidney-disease control hypertension - ischaemic heart disease - cardiac failure - vitamin D management task-force practice guidelines adolescents blood pressure antihypertensive therapy blood-pressure control renal-failure cardiovascular-disease left ventricular hypertrophy left-ventricular hypertrophy
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2D4499F9FF12]
http://linked.open...i/riv/nazevZdroje	American Journal of Hypertension
http://linked.open...in/vavai/riv/obor	FG
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	25
http://linked.open...iv/tvurceVysledku	Gilík, Jiří Seeman, Tomáš Dostalek, L.
http://linked.open...ain/vavai/riv/wos	000300385900019
http://linked.open...n/vavai/riv/zamer	Zdokonalení časné diagnostiky, prevence a léčby těžkých vrozených vývojových vad a chorob geneticky podmíněných či s genetickou dispozicí v prenatální a postnatální fázi vývoje
issn	0895-7061
number of pages	7 (xsd:int)

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