About: Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.ncbi.nlm.nih.gov/pubmed/21658646
Description	Chronic pulmonary infection with P aeruginosa develops in most patients with cystic fibrosis (CF); by adulthood 80% of patients are infected and chronic P. aeruginosa infection is the primary cause of increased morbidity and mortality in CF. Chronic infection is preceded by an intermittent stage of infection. The initial stage is characteristically followed by the gradual emergence of mucoid variants of the colonizing strains and a rise in anti-Pseudomonas antibodies. In addition to optimizing existing therapeutic strategies, effective new agents need to be identified. Studies in patients with CF are particularly challenging: the progressive nature of the disease and the wide variation in severity influence considerably the outcome of drug testing. A validated, universally accepted, and clinically useful classification of patients infected with P aeruginosa, particularly those chronically infected, is needed that can be used as both a criterion for patient selection for clinical trials and as a study endpoint. (C) 2011 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved. Chronic pulmonary infection with P aeruginosa develops in most patients with cystic fibrosis (CF); by adulthood 80% of patients are infected and chronic P. aeruginosa infection is the primary cause of increased morbidity and mortality in CF. Chronic infection is preceded by an intermittent stage of infection. The initial stage is characteristically followed by the gradual emergence of mucoid variants of the colonizing strains and a rise in anti-Pseudomonas antibodies. In addition to optimizing existing therapeutic strategies, effective new agents need to be identified. Studies in patients with CF are particularly challenging: the progressive nature of the disease and the wide variation in severity influence considerably the outcome of drug testing. A validated, universally accepted, and clinically useful classification of patients infected with P aeruginosa, particularly those chronically infected, is needed that can be used as both a criterion for patient selection for clinical trials and as a study endpoint. (C) 2011 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved. (en)
Title	Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report (en)
skos:prefLabel	Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report (en)
skos:notation	RIV/00064203:_____/11:7062!RIV12-MZ0-00064203
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	Suppl. 2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Vávrová, Věra Böhmová, Kristýna
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	190345
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/11:7062
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cystic fibrosis; Pseudomonas aeruginosa; Chronic infection; Definitions; cystic-fibrosis patients; pulmonary-function; serum antibodies; lung-disease; colonization; children; prevalence; survival; therapy (en)
http://linked.open.../riv/klicoveSlovo	Chronic infection Cystic fibrosis Definitions Pseudomonas aeruginosa children colonization cystic-fibrosis patients lung-disease prevalence pulmonary-function serum antibodies survival therapy
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[BE4B1D5B10A9]
http://linked.open...i/riv/nazevZdroje	Journal of Cystic Fibrosis
http://linked.open...in/vavai/riv/obor	FC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	10
http://linked.open...iv/tvurceVysledku	Böhmová, Kristýna Conway, S. Dumcius, S. Hjelte, L. Hoiby, N. Kollberg, H. Pressler, T. Tummler, B. Vávrová, Věra
http://linked.open...ain/vavai/riv/wos	000292068000011
issn	1569-1993
number of pages	4 (xsd:int)

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