About: Opposing and synergistic effects of cyclic mechanical stretch and alpha- or beta-adrenergic stimulation on the cardiac gap junction protein Cx43

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About: Opposing and synergistic effects of cyclic mechanical stretch and alpha- or beta-adrenergic stimulation on the cardiac gap junction protein Cx43 Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In the heart the most prominant cardiac gap junction protein is connexin43 (Cx43). Increased Cx43 expression has been indentified in cardiac hypertrophy and may contribute to arrhythmias. Gap junction channels form the basis for direct intercellular communication and are important for a regular function of all organs. It has been shawn by several working groups that beta- and alpha-adrenoreceptors might participate in hypertrophic responses and by our working group that beta- or alfa-adrenoreceptor stimulation alters Cx43 expression. In the heart the most prominant cardiac gap junction protein is connexin43 (Cx43). Increased Cx43 expression has been indentified in cardiac hypertrophy and may contribute to arrhythmias. Gap junction channels form the basis for direct intercellular communication and are important for a regular function of all organs. It has been shawn by several working groups that beta- and alpha-adrenoreceptors might participate in hypertrophic responses and by our working group that beta- or alfa-adrenoreceptor stimulation alters Cx43 expression. (en)
Title	Opposing and synergistic effects of cyclic mechanical stretch and alpha- or beta-adrenergic stimulation on the cardiac gap junction protein Cx43 Opposing and synergistic effects of cyclic mechanical stretch and alpha- or beta-adrenergic stimulation on the cardiac gap junction protein Cx43 (en)
skos:prefLabel	Opposing and synergistic effects of cyclic mechanical stretch and alpha- or beta-adrenergic stimulation on the cardiac gap junction protein Cx43 Opposing and synergistic effects of cyclic mechanical stretch and alpha- or beta-adrenergic stimulation on the cardiac gap junction protein Cx43 (en)
skos:notation	RIV/00064203:_____/10:6675!RIV11-MZ0-00064203
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Janoušek, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	277134
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/10:6675
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cyclic mechanical stretch; cardiomyocytes; connexin43; alpha-adrenoreptors; beta-adrenoreceptors (en)
http://linked.open.../riv/klicoveSlovo	connexin43 cardiomyocytes cyclic mechanical stretch alpha-adrenoreptors beta-adrenoreceptors
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[C8235F6A8650]
http://linked.open...i/riv/nazevZdroje	Pharmacological Research
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	62
http://linked.open...iv/tvurceVysledku	Janoušek, Jan Daehnert, Ingo Salameh, Aida Dhein, Stefan Karl, Sebastian Djilali, Hjalmar
http://linked.open...ain/vavai/riv/wos	000284965700006
issn	1043-6618
number of pages	8 (xsd:int)

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