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  • In the study miR-20a expression was significantly higher in the group of patients with a Gleason score of 7-10 in comparison with the group of patients with a Gleason score of 0-6 (p=0.0082). We found no statistical differences in the miRNA expressions (mir-20a, let-7a, miR-15a and miR-16) in the PCa tissue samples in comparison with the BPH tissue samples. The rresult shows that the more dedifferentiated PCa cells have a higher expression of miR-20a and this supports the oncogenic role of miR-20a in PCa carcinogenesis. The evaluation of miRNA expression could yield new information about PCa pathogenesis.
  • In the study miR-20a expression was significantly higher in the group of patients with a Gleason score of 7-10 in comparison with the group of patients with a Gleason score of 0-6 (p=0.0082). We found no statistical differences in the miRNA expressions (mir-20a, let-7a, miR-15a and miR-16) in the PCa tissue samples in comparison with the BPH tissue samples. The rresult shows that the more dedifferentiated PCa cells have a higher expression of miR-20a and this supports the oncogenic role of miR-20a in PCa carcinogenesis. The evaluation of miRNA expression could yield new information about PCa pathogenesis. (en)
Title
  • Importance of miR-20a Expression in Prostate Cancer Tissue
  • Importance of miR-20a Expression in Prostate Cancer Tissue (en)
skos:prefLabel
  • Importance of miR-20a Expression in Prostate Cancer Tissue
  • Importance of miR-20a Expression in Prostate Cancer Tissue (en)
skos:notation
  • RIV/00064203:_____/10:6538!RIV11-MZ0-00064203
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • O, Z(MSM0021620819)
http://linked.open...iv/cisloPeriodika
  • 9
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 263148
http://linked.open...ai/riv/idVysledku
  • RIV/00064203:_____/10:6538
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Prostate cancer; miRNA; miR-20a; let-7a; miR-15a; miR-16 (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GR - Řecká republika
http://linked.open...ontrolniKodProRIV
  • [939198009281]
http://linked.open...i/riv/nazevZdroje
  • Anticancer Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 30
http://linked.open...iv/tvurceVysledku
  • Eret, Viktor
  • Hora, Milan
  • Klečka, Jiří
  • Topolčan, Ondřej
  • Holubec, Luboš
  • Babjuk, Marek
  • Pešta, Martin
  • Novák, Květoslav
  • Kulda, Vlastimil
  • Stolz, Josef
  • Ludvikova, Marie
http://linked.open...ain/vavai/riv/wos
  • 000283009400050
http://linked.open...n/vavai/riv/zamer
issn
  • 0250-7005
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