About: Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Patients with near-tetraploid (karyotype: 81 - 103 chromosomes) acute lymphoblastic leukemia (NT-ALL) constitute about 1% of childhood ALL. We collected data of 36 European children with NT-ALL diagnosed since 1992. All patients reached complete remission (CR) after induction chemotherapy. Our data demonstrate immunophenotypic, cytogenetic, and molecular heterogeneity of NT-ALL and favorable prognosis of most NT-ALL across different immunophenotypic and/or genetic ALL subtypes. Patients with near-tetraploid (karyotype: 81 - 103 chromosomes) acute lymphoblastic leukemia (NT-ALL) constitute about 1% of childhood ALL. We collected data of 36 European children with NT-ALL diagnosed since 1992. All patients reached complete remission (CR) after induction chemotherapy. Our data demonstrate immunophenotypic, cytogenetic, and molecular heterogeneity of NT-ALL and favorable prognosis of most NT-ALL across different immunophenotypic and/or genetic ALL subtypes. (en)
Title	Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases (en)
skos:prefLabel	Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases (en)
skos:notation	RIV/00064203:_____/10:6291!RIV11-MZ0-00064203
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MSM0021620813), Z(MZ0VFN2005)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Mejstříková, Ester Starý, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	250599
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/10:6291
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Tetraploid acute lymphoblastic leukemia; polyploidy; childhood; classification; immunophenotyping; molecular genetics; prognosis; acute myeloid leukemias; nordic countries; expression; children; fusion; classification; reduction; diagnosis; impact; trials (en)
http://linked.open.../riv/klicoveSlovo	children classification diagnosis expression impact polyploidy reduction childhood prognosis molecular genetics acute myeloid leukemias Tetraploid acute lymphoblastic leukemia nordic countries fusion trials immunophenotyping
http://linked.open...odStatuVydavatele	DK - Dánské království
http://linked.open...ontrolniKodProRIV	[59736A0BA273]
http://linked.open...i/riv/nazevZdroje	European Journal of Haematology
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	22 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	85
http://linked.open...iv/tvurceVysledku	Mejstříková, Ester Starý, Jan Porwit, A. Matutes, E. Orfao, A. Schabath, R. Zemanová, Z. Forestier, E. Haas, OA Bertrand, Y. Attarbaschi, A. Lemez, P. Beneš, MC Castoldi, G. Garand, R. Kagialis-Girard, S. Ludwig, WD Pages, MP Pickl, W. Strobl, H. Talmant, P. van\'t Veer, MB
http://linked.open...ain/vavai/riv/wos	000282049300003
http://linked.open...n/vavai/riv/zamer	The Molecular Basis of Childhood Malignancies and Therapeutic Applications Diagnosis and treatment of inherited disorders II
issn	0902-4441
number of pages	9 (xsd:int)

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