About: Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	An increase in immunoglobulin free light chains (FLC) was recently described in several pathological conditions, including asthma. FLC pathology is classically associated with monoclonal gammopathies. Its association with allergic disorders is surprising and unexplained. We therefore tested a cohort of children with severe atopic dermatitis (SCORAD 50-80) to determine the serum levels of free kappa and lambda chains, and correlated the results with clinical status and relevant laboratory markers. Seventy-three patients with severe forms of AD, all children from 3 months to 3 years of age and ninety healthy age-matched controls were included in the study. An increase in immunoglobulin free light chains (FLC) was recently described in several pathological conditions, including asthma. FLC pathology is classically associated with monoclonal gammopathies. Its association with allergic disorders is surprising and unexplained. We therefore tested a cohort of children with severe atopic dermatitis (SCORAD 50-80) to determine the serum levels of free kappa and lambda chains, and correlated the results with clinical status and relevant laboratory markers. Seventy-three patients with severe forms of AD, all children from 3 months to 3 years of age and ninety healthy age-matched controls were included in the study. (en)
Title	Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis (en)
skos:prefLabel	Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis (en)
skos:notation	RIV/00064203:_____/10:6213!RIV11-MZ0-00064203
http://linked.open...avai/riv/aktivita	I S Z
http://linked.open...avai/riv/aktivity	I, S, Z(MSM0021620812), Z(MZ0FNM2005)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Skalická, Anna Šedivá, Anna Poloučková, Andrea Bartůňková, Jiřina Čapková, Štěpánka Vernerová, Eva Kayserová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	287029
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/10:6213
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	inflammatory diseases; ig; immediate; responses; allergy; marker; target; urine; cells (en)
http://linked.open.../riv/klicoveSlovo	responses target inflammatory diseases urine marker allergy cells ig immediate
http://linked.open...odStatuVydavatele	NO - Norské království
http://linked.open...ontrolniKodProRIV	[4233E2772B7D]
http://linked.open...i/riv/nazevZdroje	Scandinavian Journal of Immunology
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	71
http://linked.open...iv/tvurceVysledku	Poloučková, Andrea Šedivá, Anna Bartůňková, Jiřina Vernerová, Eva Čapková, Štěpánka Malinova, V. Kayserová, Jana Skalická, Anna
http://linked.open...ain/vavai/riv/wos	000275918400012
http://linked.open...n/vavai/riv/zamer	Chronická onemocnění vznikající na podkladě nepřiměřené reaktivity imunitního systému, jejich patogeneze a možnosti včasné diagnostiky a léčby Zdokonalení časné diagnostiky, prevence a léčby těžkých vrozených vývojových vad a chorob geneticky podmíněných či s genetickou dispozicí v prenatální a postnatální fázi vývoje
issn	0300-9475
number of pages	5 (xsd:int)

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