About: Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008     Goto   Sponge   NotDistinct   Permalink

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  • Assessment of minimal residual disease (MRD) has acquired a prominent position in European treatment protocols for patients with acute lymphoblastic leukemia (ALL), on the basis of its high prognostic value for predicting outcome and the possibilities for implementation of MRD diagnostics in treatment stratification. Therefore, there is an increasing need for standardization of methodologies and harmonization of terminology. The panel of experts summarized the current state of MRD diagnostics in ALL and developed recommendations on the minimal technical requirements that should be fulfilled before implementation of MRD diagnostics into clinical trials. Finally, a common terminology for a standard description of MRD response and monitoring was established.
  • Assessment of minimal residual disease (MRD) has acquired a prominent position in European treatment protocols for patients with acute lymphoblastic leukemia (ALL), on the basis of its high prognostic value for predicting outcome and the possibilities for implementation of MRD diagnostics in treatment stratification. Therefore, there is an increasing need for standardization of methodologies and harmonization of terminology. The panel of experts summarized the current state of MRD diagnostics in ALL and developed recommendations on the minimal technical requirements that should be fulfilled before implementation of MRD diagnostics into clinical trials. Finally, a common terminology for a standard description of MRD response and monitoring was established. (en)
Title
  • Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008
  • Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008 (en)
skos:prefLabel
  • Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008
  • Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008 (en)
skos:notation
  • RIV/00064203:_____/10:6209!RIV11-MZ0-00064203
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 289649
http://linked.open...ai/riv/idVysledku
  • RIV/00064203:_____/10:6209
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • acute lymphoblastic leukemia; ALL; minimal residual disease; MRD; flow cytometry; PCR; acute lymphoblastic-leukemia; minimal-residual-disease; polymerase-chain-reaction; time quantitative pcr; precursor-b-all; acute promyelocytic leukemia; bone-marrow-transplantation; ig/tcr gene rearrangements; stem-cell transplantation; flow-cytometry (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [613AB542223E]
http://linked.open...i/riv/nazevZdroje
  • Leukemia
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 24
http://linked.open...iv/tvurceVysledku
  • Baruchel, A.
  • Pieters, R.
  • Schrauder, A.
  • Starý, Jan
  • von Stackelberg, A.
  • Bassan, R.
  • Dombret, H.
  • Hoelzer, D.
  • Benoit, Y.
  • Biondi, A.
  • Schmiegelow, K.
  • Schrappe, M.
  • Asnafi, V.
  • Bruggemann, M.
  • van Dongen, JJM
  • Kneba, M.
  • Cave, H.
  • Dworzak, M.
  • Henze, G.
  • Fielding, AK
  • Foa, R.
  • Gokbuget, N.
  • Goldstone, AH
  • Goulden, N.
  • Janka-Schaub, GE
  • Macintyre, E. A.
  • Ottmann, OG
  • Pfeifer, H.
  • Raff, T.
  • Rambaldi, A.
  • Ribera, JM
  • Spinelli, O.
http://linked.open...ain/vavai/riv/wos
  • 000275399600004
issn
  • 0887-6924
number of pages
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