About: Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma     Goto   Sponge   NotDistinct   Permalink

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  • Anaplastic large cell lymphoma (ALCL) is a main type of T-cell lymphomas and comprises three distinct entities: systemic anaplastic lymphoma kinase (ALK) positive, systemic ALK(-) and cutaneous ALK(-) ALCL (cALCL). Little is known about their pathogenesis and their cellular origin, and morphological and immunophenotypical overlap exists between ALK(-) ALCL and classical Hodgkin lymphoma (cHL). We conducted gene expression profiling of microdissected lymphoma cells of five ALK(+) and four ALK(-) systemic ALCL, seven cALCL and sixteen cHL, and of eight subsets of normal T and NK cells.
  • Anaplastic large cell lymphoma (ALCL) is a main type of T-cell lymphomas and comprises three distinct entities: systemic anaplastic lymphoma kinase (ALK) positive, systemic ALK(-) and cutaneous ALK(-) ALCL (cALCL). Little is known about their pathogenesis and their cellular origin, and morphological and immunophenotypical overlap exists between ALK(-) ALCL and classical Hodgkin lymphoma (cHL). We conducted gene expression profiling of microdissected lymphoma cells of five ALK(+) and four ALK(-) systemic ALCL, seven cALCL and sixteen cHL, and of eight subsets of normal T and NK cells. (en)
Title
  • Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma
  • Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma (en)
skos:prefLabel
  • Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma
  • Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma (en)
skos:notation
  • RIV/00064203:_____/09:5332!RIV10-MZ0-00064203
http://linked.open...avai/riv/aktivita
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  • V
http://linked.open...iv/cisloPeriodika
  • 11
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  • 316052
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  • RIV/00064203:_____/09:5332
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  • anaplastic large cell lymphoma; Hodgkin lymphoma; gene expression profiling; lymphoma pathogenesis; nf-kappa-b; reed-sternberg cells; t-cell; classical hodgkin; molecular-biology; cdna arrays; disease; transcription; promoter; features (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [6C2136AFCD79]
http://linked.open...i/riv/nazevZdroje
  • Leukemia
http://linked.open...in/vavai/riv/obor
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http://linked.open...v/svazekPeriodika
  • 23
http://linked.open...iv/tvurceVysledku
  • Kodet, Roman
  • Klapper, W.
  • Eckerle, S.
  • Paulli, M.
  • Bohle, V.
  • Brauninger, A.
  • Brune, V.
  • Chaubert, AB
  • Doring, C.
  • Falini, B.
  • Hansmann, M. L.
  • Kuppers, R.
  • Metzler, D.
  • Sundstrom, C.
  • Tiacci, E.
  • Willenbrock, K.
http://linked.open...ain/vavai/riv/wos
  • 000271666000021
issn
  • 0887-6924
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