About: Heart failure treated with low-dose milrinone in a full-term newborn

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://pmr.cuni.cz/volume-113-2012-no-1
Description	A term newborn with a hypocontractile myocardium complicating persistent pulmonary hypertension of the newborn was successfully treated with a low-dose phosphodiesterase III inhibitor milrinone. Echocardiography diagnosed heart failure with a left ventricular ejection fraction of 35% and a left ventricular shortening fraction of 18% and severe persistent pulmonary hypertension of the newborn with oxygenation index of 28. Milrinone was started at an initial dose of 50 mcg/kg, followed by continuous infusion of 0.20 mcg/kg/min. With lowdose milrinone oxygenation index decreased to 3 within 6 hours, left ventricular ejection fraction and left ventricular shortening fraction increased to 57%, and 30%, respectively. Low doses of milrinone might be promising in the treatment of heart failure and persistent pulmonary hypertension of the newborn in term newborns. A term newborn with a hypocontractile myocardium complicating persistent pulmonary hypertension of the newborn was successfully treated with a low-dose phosphodiesterase III inhibitor milrinone. Echocardiography diagnosed heart failure with a left ventricular ejection fraction of 35% and a left ventricular shortening fraction of 18% and severe persistent pulmonary hypertension of the newborn with oxygenation index of 28. Milrinone was started at an initial dose of 50 mcg/kg, followed by continuous infusion of 0.20 mcg/kg/min. With lowdose milrinone oxygenation index decreased to 3 within 6 hours, left ventricular ejection fraction and left ventricular shortening fraction increased to 57%, and 30%, respectively. Low doses of milrinone might be promising in the treatment of heart failure and persistent pulmonary hypertension of the newborn in term newborns. (en)
Title	Heart failure treated with low-dose milrinone in a full-term newborn Heart failure treated with low-dose milrinone in a full-term newborn (en)
skos:prefLabel	Heart failure treated with low-dose milrinone in a full-term newborn Heart failure treated with low-dose milrinone in a full-term newborn (en)
skos:notation	RIV/00064190:_____/12:#0000359!RIV13-MZ0-00064190
http://linked.open...avai/riv/aktivita	I V
http://linked.open...avai/riv/aktivity	I, V
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Janota, Jan Šebková, Sylva Zemanová, Patricia
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Thomayerova nemocnice
http://linked.open...dnocenehoVysledku	138722
http://linked.open...ai/riv/idVysledku	RIV/00064190:_____/12:#0000359
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cardiotonic; heart failure; people; newborn; syndrome of persistent fetal circulation; vasodilators; milrinone (en)
http://linked.open.../riv/klicoveSlovo	newborn people heart failure cardiotonic milrinone syndrome of persistent fetal circulation vasodilators
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[1B5F08D9E3A6]
http://linked.open...i/riv/nazevZdroje	Prague medical report
http://linked.open...in/vavai/riv/obor	FG
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	113
http://linked.open...iv/tvurceVysledku	Janota, Jan Tomek, Jiří Zemanová, Patricia Šebková, Sylva
issn	1214-6994
number of pages	8 (xsd:int)

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