About: Rituximab-induced coagulopathy     Goto   Sponge   NotDistinct   Permalink

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Description
  • Rituximab is a chimeric monoclonal antibody against CD20 that became standard care of B-cell malignancies and some autoimmune disorders. Rituximab exhibits low toxicity profile, the most common side effects such as fever, chills or rigors occur typically within few hours of initiation of the first infusion. Delayed side effects are far more rare and include transitory neutropenia, progressive multifocal leukoencephalopathy or intersticial pneumonitis. One of extremely rare complications is rituximab-induced coagulopathy. It is self-limited event occurring early after the start of rituximab treatment. This phenomenon is not preceded by clinical symptomatology of cytokine releasing syndrome and till nowadays it was observed only in patients with WM or HCL.
  • Rituximab is a chimeric monoclonal antibody against CD20 that became standard care of B-cell malignancies and some autoimmune disorders. Rituximab exhibits low toxicity profile, the most common side effects such as fever, chills or rigors occur typically within few hours of initiation of the first infusion. Delayed side effects are far more rare and include transitory neutropenia, progressive multifocal leukoencephalopathy or intersticial pneumonitis. One of extremely rare complications is rituximab-induced coagulopathy. It is self-limited event occurring early after the start of rituximab treatment. This phenomenon is not preceded by clinical symptomatology of cytokine releasing syndrome and till nowadays it was observed only in patients with WM or HCL. (en)
Title
  • Rituximab-induced coagulopathy
  • Rituximab-induced coagulopathy (en)
skos:prefLabel
  • Rituximab-induced coagulopathy
  • Rituximab-induced coagulopathy (en)
skos:notation
  • RIV/00064173:_____/12:43896702!RIV13-MZ0-00064173
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
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  • 165712
http://linked.open...ai/riv/idVysledku
  • RIV/00064173:_____/12:43896702
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  • complication; thrombocytopenia; DIC; coagulopathy; rituximab (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [B92770FDF149]
http://linked.open...i/riv/nazevZdroje
  • Leukemia & Lymphoma
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 53
http://linked.open...iv/tvurceVysledku
  • Kozák, Tomáš
  • Novák, Jan
  • Móciková, Heidi
  • Pavlíček, Petr
http://linked.open...ain/vavai/riv/wos
  • 000309475600036
issn
  • 1042-8194
number of pages
http://bibframe.org/vocab/doi
  • 10.3109/10428194.2012.682313
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