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  • Patients with moderate to severe psoriasis are undertreated. To solve this persistent problem, the consensus programme was performed to define goals for treatment of plaque psoriasis with systemic therapy and to improve patient care. An expert consensus meeting and a collaborative Delphi procedure were carried out. Nineteen dermatologists from different European countries met for a face-to-face discussion and defined items through a four-round Delphi process. Severity of plaque psoriasis was graded into mild and moderate to severe disease. Mild disease was defined as body surface area (BSA) 10 or PASI > 10) and DLQI > 10. Special clinical situations may change mild psoriasis to moderate to severe including involvement of visible areas or severe nail involvement. For systemic therapy of plaque psoriasis two treatment phases were defined: (1) induction phase as the treatment period until week 16; however, depending on the type of drug and dose regimen used, this phase may be extended until week 24 and (2) maintenance phase for all drugs was defined as the treatment period after the induction phase. For the definition of treatment goals in plaque psoriasis, the change of PASI from baseline until the time of evaluation (DeltaPASI) and the absolute DLQI were used. After induction and during maintenance therapy, treatment can be continued if reduction in PASI is >/=75%. The treatment regimen should be modified if improvement of PASI is <50%. In a situation where the therapeutic response improved >/=50% but <75%, as assessed by PASI, therapy should be modified if the DLQI is >5 but can be continued if the DLQI is
  • Patients with moderate to severe psoriasis are undertreated. To solve this persistent problem, the consensus programme was performed to define goals for treatment of plaque psoriasis with systemic therapy and to improve patient care. An expert consensus meeting and a collaborative Delphi procedure were carried out. Nineteen dermatologists from different European countries met for a face-to-face discussion and defined items through a four-round Delphi process. Severity of plaque psoriasis was graded into mild and moderate to severe disease. Mild disease was defined as body surface area (BSA) 10 or PASI > 10) and DLQI > 10. Special clinical situations may change mild psoriasis to moderate to severe including involvement of visible areas or severe nail involvement. For systemic therapy of plaque psoriasis two treatment phases were defined: (1) induction phase as the treatment period until week 16; however, depending on the type of drug and dose regimen used, this phase may be extended until week 24 and (2) maintenance phase for all drugs was defined as the treatment period after the induction phase. For the definition of treatment goals in plaque psoriasis, the change of PASI from baseline until the time of evaluation (DeltaPASI) and the absolute DLQI were used. After induction and during maintenance therapy, treatment can be continued if reduction in PASI is >/=75%. The treatment regimen should be modified if improvement of PASI is <50%. In a situation where the therapeutic response improved >/=50% but <75%, as assessed by PASI, therapy should be modified if the DLQI is >5 but can be continued if the DLQI is (en)
  • Patients with moderate to severe psoriasis are undertreated. To solve this persistent problem, the consensus programme was performed to define goals for treatment of plaque psoriasis with systemic therapy and to improve patient care. An expert consensus meeting and a collaborative Delphi procedure were carried out. Nineteen dermatologists from different European countries met for a face-to-face discussion and defined items through a four-round Delphi process. Severity of plaque psoriasis was graded into mild and moderate to severe disease. Mild disease was defined as body surface area (BSA) 10 or PASI > 10) and DLQI > 10. Special clinical situations may change mild psoriasis to moderate to severe including involvement of visible areas or severe nail involvement. For systemic therapy of plaque psoriasis two treatment phases were defined: (1) induction phase as the treatment period until week 16; however, depending on the type of drug and dose regimen used, this phase may be extended until week 24 and (2) maintenance phase for all drugs was defined as the treatment period after the induction phase. For the definition of treatment goals in plaque psoriasis, the change of PASI from baseline until the time of evaluation (DeltaPASI) and the absolute DLQI were used. After induction and during maintenance therapy, treatment can be continued if reduction in PASI is >/=75%. The treatment regimen should be modified if improvement of PASI is <50%. In a situation where the therapeutic response improved >/=50% but <75%, as assessed by PASI, therapy should be modified if the DLQI is >5 but can be continued if the DLQI is (cs)
Title
  • Definition of treatment goals for moderate to severe psoriasis: a European consensus
  • Definition of treatment goals for moderate to severe psoriasis: a European consensus (en)
  • Definition of treatment goals for moderate to severe psoriasis: a European consensus (cs)
skos:prefLabel
  • Definition of treatment goals for moderate to severe psoriasis: a European consensus
  • Definition of treatment goals for moderate to severe psoriasis: a European consensus (en)
  • Definition of treatment goals for moderate to severe psoriasis: a European consensus (cs)
skos:notation
  • RIV/00064173:_____/11:#0000290!RIV12-MZ0-00064173
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • N
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 193119
http://linked.open...ai/riv/idVysledku
  • RIV/00064173:_____/11:#0000290
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Psoriasis, Treatment goals, Severity, Patient care, Consensus (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [60D30D8D2CCB]
http://linked.open...i/riv/nazevZdroje
  • Archives of Dermatological Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 303
http://linked.open...iv/tvurceVysledku
  • Arenberger, P.
  • Antoniou, C.
  • Balieva, F.
  • Bylaite, M.
  • Correia, O.
  • Dauden, E.
  • Franke, J.
  • Gisondi, P.
  • Griffiths, CEM
  • Iversen, L.
  • Kemeny, L.
  • Kragballe, K.
  • Lahfa, M.
  • Mrowietz, U.
  • Nast, A.
  • Nijsten, T.
  • Rantanen, T.
  • Reich, A.
  • Reich, K.
  • Rosenbach, T.
  • Segaert, S.
  • Smith, C.
  • Spuls, P.
  • Talme, T.
  • Volc-Platzer, B.
  • Yawalkar, N.
issn
  • 0340-3696
number of pages
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