About: Efficacy of FiO(2) Increase During the Initial Resuscitation of Premature Infants < 29 Weeks: An Observational Study     Goto   Sponge   NotDistinct   Permalink

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  • Objective: To evaluate the heart rate (HR) and oxygen saturation (SpO(2)) at 15-second. intervals within 60 seconds after incremental increases of fractional inspired oxygen (FiO(2)) during resuscitation of infants younger than 29 weeks requiring two different forms of ventilatory support. Study design: Retrospective observational study. Methods: Forty-three infants were stabilized, 14 by continuous positive airway pressure exclusively (CPAP group), and 29 by positive pressure ventilation (PPV group). Both groups received ventilatory support in a special bed with two cameras enabling the evaluation of all interventions including HR, SpO(2), FiO(2), positive inflation pressure, and positive end-expiratory pressure values. FiO(2) was commenced at 0.30 and titrated in 0.1-0.2 increments every 30-60 seconds. The relationships between the incremental increases of FiO(2) and related SpO(2) and HR changes were evaluated. Results: Although there was an inverse correlation between initial FiO(2) and SpO(2) in both groups, a significant positive correlation between the incremental increase of FiO(2) and SpO(2) changes after 30 seconds was found only in the CPAP group. Only higher initial levels of FiO(2) had a positive effect on the improvement in SpO(2) in the PPV group. Conclusion: The efficacy of FiO(2) titration in 0.1-0.2 increments may be attenuated and delayed in extremely preterm infants required PPV during the first 6 minutes of life.
  • Objective: To evaluate the heart rate (HR) and oxygen saturation (SpO(2)) at 15-second. intervals within 60 seconds after incremental increases of fractional inspired oxygen (FiO(2)) during resuscitation of infants younger than 29 weeks requiring two different forms of ventilatory support. Study design: Retrospective observational study. Methods: Forty-three infants were stabilized, 14 by continuous positive airway pressure exclusively (CPAP group), and 29 by positive pressure ventilation (PPV group). Both groups received ventilatory support in a special bed with two cameras enabling the evaluation of all interventions including HR, SpO(2), FiO(2), positive inflation pressure, and positive end-expiratory pressure values. FiO(2) was commenced at 0.30 and titrated in 0.1-0.2 increments every 30-60 seconds. The relationships between the incremental increases of FiO(2) and related SpO(2) and HR changes were evaluated. Results: Although there was an inverse correlation between initial FiO(2) and SpO(2) in both groups, a significant positive correlation between the incremental increase of FiO(2) and SpO(2) changes after 30 seconds was found only in the CPAP group. Only higher initial levels of FiO(2) had a positive effect on the improvement in SpO(2) in the PPV group. Conclusion: The efficacy of FiO(2) titration in 0.1-0.2 increments may be attenuated and delayed in extremely preterm infants required PPV during the first 6 minutes of life. (en)
Title
  • Efficacy of FiO(2) Increase During the Initial Resuscitation of Premature Infants < 29 Weeks: An Observational Study
  • Efficacy of FiO(2) Increase During the Initial Resuscitation of Premature Infants < 29 Weeks: An Observational Study (en)
skos:prefLabel
  • Efficacy of FiO(2) Increase During the Initial Resuscitation of Premature Infants < 29 Weeks: An Observational Study
  • Efficacy of FiO(2) Increase During the Initial Resuscitation of Premature Infants < 29 Weeks: An Observational Study (en)
skos:notation
  • RIV/00064165:_____/13:10192832!RIV14-MZ0-00064165
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • N
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
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  • 72023
http://linked.open...ai/riv/idVysledku
  • RIV/00064165:_____/13:10192832
http://linked.open...riv/jazykVysledku
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  • ventilatory support; FiO(2) titration; extremely premature infants; delivery room (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • TW - Čínská republika (Tchaj-wan)
http://linked.open...ontrolniKodProRIV
  • [188583AB6A50]
http://linked.open...i/riv/nazevZdroje
  • Pediatrics and Neonatology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 54
http://linked.open...iv/tvurceVysledku
  • Plavka, Richard
  • Lamberská, Tereza
  • Vankova, Jana
http://linked.open...ain/vavai/riv/wos
  • 000329534200006
issn
  • 1875-9572
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.pedneo.2013.06.006
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