About: Validity of the Montreal Cognitive Assessment in the Detection of Cognitive Dysfunction in Huntington's Disease

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About: Validity of the Montreal Cognitive Assessment in the Detection of Cognitive Dysfunction in Huntington's Disease Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1080/09084282.2012.670158
Description	The purpose of this study was to assess the convergent and discriminative validity of the Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive dysfunction in Huntington's disease (HD). Twenty HD patients with cognitive deficit and 23 normal controls (NC) without cognitive deficit were matched for age, sex, and education. The mean MoCA score was 20.5 (SD=5.5) in HD and 27.5 (SD=2.2) in NC. The MoCA correlated in both samples with the brief cognitive battery composite score (r=.81, p<.001). With the screening and diagnostic cutoff scores determined at <26 points, the MoCA showed a sensitivity of 94% and a specificity of 84% in the detection of cognitive dysfunction in HD. The area under the receiver-operating characteristics curve (95% confidence interval) for the MoCA was 0.90 (0.8090.997), p<.001. Our results show that the MoCA is a suitable tool for assessing cognitive dysfunction in patients with HD. The purpose of this study was to assess the convergent and discriminative validity of the Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive dysfunction in Huntington's disease (HD). Twenty HD patients with cognitive deficit and 23 normal controls (NC) without cognitive deficit were matched for age, sex, and education. The mean MoCA score was 20.5 (SD=5.5) in HD and 27.5 (SD=2.2) in NC. The MoCA correlated in both samples with the brief cognitive battery composite score (r=.81, p<.001). With the screening and diagnostic cutoff scores determined at <26 points, the MoCA showed a sensitivity of 94% and a specificity of 84% in the detection of cognitive dysfunction in HD. The area under the receiver-operating characteristics curve (95% confidence interval) for the MoCA was 0.90 (0.8090.997), p<.001. Our results show that the MoCA is a suitable tool for assessing cognitive dysfunction in patients with HD. (en)
Title	Validity of the Montreal Cognitive Assessment in the Detection of Cognitive Dysfunction in Huntington's Disease Validity of the Montreal Cognitive Assessment in the Detection of Cognitive Dysfunction in Huntington's Disease (en)
skos:prefLabel	Validity of the Montreal Cognitive Assessment in the Detection of Cognitive Dysfunction in Huntington's Disease Validity of the Montreal Cognitive Assessment in the Detection of Cognitive Dysfunction in Huntington's Disease (en)
skos:notation	RIV/00064165:_____/13:10189449!RIV14-MZ0-00064165
http://linked.open...avai/riv/aktivita	V Z
http://linked.open...avai/riv/aktivity	V, Z(MSM0021620849)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Bezdíček, Ondřej Růžička, Evžen Roth, Jan Majerová, Veronika Nikolai, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Všeobecná fakultní nemocnice v Praze / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	113558
http://linked.open...ai/riv/idVysledku	RIV/00064165:_____/13:10189449
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Montreal Cognitive Assessment; Huntington's disease; Dementia (en)
http://linked.open.../riv/klicoveSlovo	Montreal Cognitive Assessment Dementia Huntington's disease
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[79216A127663]
http://linked.open...i/riv/nazevZdroje	Applied Neuropsychology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	20
http://linked.open...iv/tvurceVysledku	Majerová, Veronika Roth, Jan Růžička, Evžen Novák, Marek Nikolai, Tomáš Bezdíček, Ondřej
http://linked.open...ain/vavai/riv/wos	000316380000005
http://linked.open...n/vavai/riv/zamer	Neuropsychiatrické aspekty neurodegenerativních onemocnění
issn	0908-4282
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1080/09084282.2012.670158

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