About: Intracellular Cytokine Production in Peripheral Blood Lymphocytes: A Comparison of Values in Infertile and Fertile Women

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About: Intracellular Cytokine Production in Peripheral Blood Lymphocytes: A Comparison of Values in Infertile and Fertile Women Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1111/j.1600-0897.2010.00959.x
Description	To analyze the relation of the fertility and pregnancy of women of childbearing age to the intracellular (IC) production of tumor necrosis factor alpha (TNF-alpha), interferon gamma (IFN-gamma), and interleukins 2 and 4 (IL-2 and IL-4). Intracellular cytokine production in peripheral blood CD3(+) CD4(+)lymphocytes was analyzed by flow cytometry in 185 women being treated for infertility and 50 fertile women of childbearing age. Infertile women have a significantly higher IC production of TNF-alpha, IFN-gamma, IL-2, and IL-4 and higher ratios of TNF-alpha/IL-2, TNF-alpha/IL-4, and TNF-alpha/IFN-gamma compared to the fertile women. Cytokines produced by Th lymphocytes are important in orchestrating the immune response during conception, and Th-cell dysregulation could be a reason for infertility. To analyze the relation of the fertility and pregnancy of women of childbearing age to the intracellular (IC) production of tumor necrosis factor alpha (TNF-alpha), interferon gamma (IFN-gamma), and interleukins 2 and 4 (IL-2 and IL-4). Intracellular cytokine production in peripheral blood CD3(+) CD4(+)lymphocytes was analyzed by flow cytometry in 185 women being treated for infertility and 50 fertile women of childbearing age. Infertile women have a significantly higher IC production of TNF-alpha, IFN-gamma, IL-2, and IL-4 and higher ratios of TNF-alpha/IL-2, TNF-alpha/IL-4, and TNF-alpha/IFN-gamma compared to the fertile women. Cytokines produced by Th lymphocytes are important in orchestrating the immune response during conception, and Th-cell dysregulation could be a reason for infertility. (en)
Title	Intracellular Cytokine Production in Peripheral Blood Lymphocytes: A Comparison of Values in Infertile and Fertile Women Intracellular Cytokine Production in Peripheral Blood Lymphocytes: A Comparison of Values in Infertile and Fertile Women (en)
skos:prefLabel	Intracellular Cytokine Production in Peripheral Blood Lymphocytes: A Comparison of Values in Infertile and Fertile Women Intracellular Cytokine Production in Peripheral Blood Lymphocytes: A Comparison of Values in Infertile and Fertile Women (en)
skos:notation	RIV/00064165:_____/11:9496!RIV12-MZ0-00064165
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MSM0021620807)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kalousová, Marta Jarošová, Radka Horká, Petra Zima, Tomáš Malíčková, Karin Janatková, Ivana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Všeobecná fakultní nemocnice v Praze / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	205553
http://linked.open...ai/riv/idVysledku	RIV/00064165:_____/11:9496
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cytokine; flow cytometry; infertility (en)
http://linked.open.../riv/klicoveSlovo	Cytokine flow cytometry infertility
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[A8ECD9A9200E]
http://linked.open...i/riv/nazevZdroje	American Journal of Reproductive Immunology
http://linked.open...in/vavai/riv/obor	FK
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	65
http://linked.open...iv/tvurceVysledku	Horká, Petra Kalousová, Marta Malíčková, Karin Zima, Tomáš Jarošová, Radka Janatková, Ivana Marečková, Helena
http://linked.open...n/vavai/riv/zamer	Metabolické, endokrinní a genetické aspekty prevence, diagnostiky a terapie kardiovaskulárních, cerebrovaskulárních a renovaskulárních onemocnění
issn	1046-7408
number of pages	4 (xsd:int)

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